Cancer slice

Kidney Renal Clear Cell Carcinoma (TCGA, PanCancer Atlas)

75 records, 7 actionable signals, and 75 hotspot records in this source-aligned cancer slice.

Variant	Cancer	Evidence	Frequency	Sources
KRAS p.G12C substitution	CCRCC	DriverHotspotActionable	0.25%	cBioPortal, TCGA Pan-Cancer Atlas
KRAS p.A59G substitution	CCRCC	DriverHotspotActionable	0.25%	cBioPortal, TCGA Pan-Cancer Atlas
MET p.V1070E substitution	CCRCC	DriverHotspotActionable	0.25%	cBioPortal, TCGA Pan-Cancer Atlas
PIK3CA p.G1049R substitution	CCRCC	DriverHotspotActionable	0.25%	cBioPortal, TCGA Pan-Cancer Atlas
PIK3CA p.H1047R substitution	CCRCC	DriverHotspotActionable	0.25%	cBioPortal, TCGA Pan-Cancer Atlas
PIK3CA p.H1047L substitution	CCRCC	DriverHotspotActionable	0.25%	cBioPortal, TCGA Pan-Cancer Atlas
PIK3CA p.E545K substitution	CCRCC	DriverHotspotActionable	0.25%	cBioPortal, TCGA Pan-Cancer Atlas
VHL p.H115N substitution	CCRCC	DriverHotspot	1.00%	cBioPortal, TCGA Pan-Cancer Atlas
MTOR p.T1977R substitution	CCRCC	DriverHotspot	0.75%	cBioPortal, TCGA Pan-Cancer Atlas
VHL p.L169P substitution	CCRCC	DriverHotspot	0.75%	cBioPortal, TCGA Pan-Cancer Atlas
MTOR p.L1460P substitution	CCRCC	DriverHotspot	0.50%	cBioPortal, TCGA Pan-Cancer Atlas
MTOR p.C1483F substitution	CCRCC	DriverHotspot	0.50%	cBioPortal, TCGA Pan-Cancer Atlas
VHL p.W88* substitution	CCRCC	DriverHotspot	0.50%	cBioPortal, TCGA Pan-Cancer Atlas
VHL p.R161* substitution	CCRCC	DriverHotspot	0.50%	cBioPortal, TCGA Pan-Cancer Atlas
VHL p.S65* substitution	CCRCC	DriverHotspot	0.50%	cBioPortal, TCGA Pan-Cancer Atlas
VHL p.L158V substitution	CCRCC	DriverHotspot	0.50%	cBioPortal, TCGA Pan-Cancer Atlas
VHL p.V74D substitution	CCRCC	DriverHotspot	0.50%	cBioPortal, TCGA Pan-Cancer Atlas
VHL p.S68* substitution	CCRCC	DriverHotspot	0.50%	cBioPortal, TCGA Pan-Cancer Atlas
VHL p.D121Y substitution	CCRCC	DriverHotspot	0.50%	cBioPortal, TCGA Pan-Cancer Atlas
VHL p.N78D substitution	CCRCC	DriverHotspot	0.50%	cBioPortal, TCGA Pan-Cancer Atlas
VHL p.S111N substitution	CCRCC	DriverHotspot	0.50%	cBioPortal, TCGA Pan-Cancer Atlas
VHL p.I151T substitution	CCRCC	DriverHotspot	0.50%	cBioPortal, TCGA Pan-Cancer Atlas
DIS3 p.L767F substitution	CCRCC	DriverHotspot	0.25%	cBioPortal, TCGA Pan-Cancer Atlas
ATM p.R250* substitution	CCRCC	DriverHotspot	0.25%	cBioPortal, TCGA Pan-Cancer Atlas
DIS3 p.R780S substitution	CCRCC	DriverHotspot	0.25%	cBioPortal, TCGA Pan-Cancer Atlas
MTOR p.M2327I substitution	CCRCC	DriverHotspot	0.25%	cBioPortal, TCGA Pan-Cancer Atlas
MTOR p.T1977K substitution	CCRCC	DriverHotspot	0.25%	cBioPortal, TCGA Pan-Cancer Atlas
NFE2L2 p.G81D substitution	CCRCC	DriverHotspot	0.25%	cBioPortal, TCGA Pan-Cancer Atlas
MTOR p.C1483Y substitution	CCRCC	DriverHotspot	0.25%	cBioPortal, TCGA Pan-Cancer Atlas
NFE2L2 p.E82D substitution	CCRCC	DriverHotspot	0.25%	cBioPortal, TCGA Pan-Cancer Atlas
MTOR p.A1459P substitution	CCRCC	DriverHotspot	0.25%	cBioPortal, TCGA Pan-Cancer Atlas
NFE2L2 p.L30H substitution	CCRCC	DriverHotspot	0.25%	cBioPortal, TCGA Pan-Cancer Atlas
MTOR p.V2006L substitution	CCRCC	DriverHotspot	0.25%	cBioPortal, TCGA Pan-Cancer Atlas
MTOR p.S2215Y substitution	CCRCC	DriverHotspot	0.25%	cBioPortal, TCGA Pan-Cancer Atlas
MTOR p.I2500M substitution	CCRCC	DriverHotspot	0.25%	cBioPortal, TCGA Pan-Cancer Atlas
MTOR p.F1888L substitution	CCRCC	DriverHotspot	0.25%	cBioPortal, TCGA Pan-Cancer Atlas
NFE2L2 p.D29H substitution	CCRCC	DriverHotspot	0.25%	cBioPortal, TCGA Pan-Cancer Atlas
PTEN p.L146* frameshift	CCRCC	DriverHotspot	0.25%	cBioPortal, TCGA Pan-Cancer Atlas
PTEN p.S170N substitution	CCRCC	DriverHotspot	0.25%	cBioPortal, TCGA Pan-Cancer Atlas
VHL p.G114A substitution	CCRCC	DriverHotspot	0.25%	cBioPortal, TCGA Pan-Cancer Atlas