Glossary

Terms used in the atlas

Plain-language definitions for mutation, evidence, and provenance vocabulary.

A record with associated drug, trial, or curated actionability signal in the seed data. It is not a treatment recommendation.

A mutation or gene-level event believed to contribute to tumor biology in the source evidence.

A recurrently altered residue or locus observed across cancer cohorts.

Human Genome Variation Society notation for describing sequence variants.

A controlled vocabulary for cancer type and tissue lineage.

The source, citation, date, and transformation trail behind a record.

A high-level label summarizing how often a mutation appears in the seed catalog.

The atlas is designed for exploration and hypothesis generation, not diagnosis or clinical decision-making.

A tumor-acquired alteration. This atlas may also contain germline-oriented public records from ClinVar where represented in the seed.

The detail panel in Explore showing mutation, cohort, source, link, and export context for a selected record.