cBioPortal
Somatic mutation observations from public cancer genomics studies.
Used for cohort frequencies, sample counts, study links, and gene-level mutation context.
Every record keeps its source databases, citation identifiers, links, and generation date visible. Seed catalog freshness: Feb 4, 2026.
Somatic mutation observations from public cancer genomics studies.
Used for cohort frequencies, sample counts, study links, and gene-level mutation context.
Public harmonized cancer cohort context represented through cBioPortal-derived records.
Used as a high-level public cohort backbone for cancer-type observations.
Recurrent amino-acid positions observed across cancer cohorts.
Used as hotspot evidence and a prioritization signal for variant pages.
Variant-level clinical significance assertions and identifier context.
Used for clinical-significance labels and variation links where present.
Cancer type vocabulary and code mapping.
Used to make cancer-type labels and route groupings consistent.
Driver gene knowledgebase referenced by the seed build metadata.
Kept as a provenance hook for driver-gene enrichment.
Open variant interpretation evidence model.
Supported as a future enrichment target and modeled in schema-compatible fields.
Trial identifier surface for therapy and variant context.
Supported through NCT fields and links where available.
Public regulatory approval context.
Supported as an indication field and future data adapter.