Cancer slice
Lung Adenocarcinoma (TCGA, PanCancer Atlas)
338 records, 64 actionable signals, and 337 hotspot records in this source-aligned cancer slice.
| Variant | Cancer | Evidence | Frequency | Sources |
|---|---|---|---|---|
| KRAS p.G12C | LUAD | DriverHotspotActionable | 12.4% | cBioPortal, TCGA Pan-Cancer Atlas |
| KRAS p.G12V | LUAD | DriverHotspotActionable | 7.1% | cBioPortal, TCGA Pan-Cancer Atlas |
| EGFR p.L858R | LUAD | DriverHotspotActionable | 4.1% | cBioPortal, TCGA Pan-Cancer Atlas |
| KRAS p.G12D | LUAD | DriverHotspotActionable | 3.5% | cBioPortal, TCGA Pan-Cancer Atlas |
| KRAS p.G12A | LUAD | DriverHotspotActionable | 3.0% | cBioPortal, TCGA Pan-Cancer Atlas |
| EGFR p.E746_A750del | LUAD | DriverHotspotActionable | 1.9% | cBioPortal, TCGA Pan-Cancer Atlas |
| BRAF p.V600E | LUAD | DriverHotspotActionable | 1.6% | cBioPortal, TCGA Pan-Cancer Atlas |
| KRAS p.G13C | LUAD | DriverHotspotActionable | 1.2% | cBioPortal, TCGA Pan-Cancer Atlas |
| PIK3CA p.E545K | LUAD | DriverHotspotActionable | 1.1% | cBioPortal, TCGA Pan-Cancer Atlas |
| BRAF p.G469V | LUAD | DriverHotspotActionable | 0.88% | cBioPortal, TCGA Pan-Cancer Atlas |
| BRAF p.G466V | LUAD | DriverHotspotActionable | 0.88% | cBioPortal, TCGA Pan-Cancer Atlas |
| EGFR p.E746_A750del | LUAD | DriverHotspotActionable | 0.88% | cBioPortal, TCGA Pan-Cancer Atlas |
| KRAS p.G12S | LUAD | DriverHotspotActionable | 0.88% | cBioPortal, TCGA Pan-Cancer Atlas |
| PIK3CA p.E542K | LUAD | DriverHotspotActionable | 0.71% | cBioPortal, TCGA Pan-Cancer Atlas |
| EGFR p.L861Q | LUAD | DriverHotspotActionable | 0.53% | cBioPortal, TCGA Pan-Cancer Atlas |
| BRAF p.N581S | LUAD | DriverHotspotActionable | 0.53% | cBioPortal, TCGA Pan-Cancer Atlas |
| EGFR p.E709_T710delinsD | LUAD | DriverHotspotActionable | 0.53% | cBioPortal, TCGA Pan-Cancer Atlas |
| KRAS p.Q61L | LUAD | DriverHotspotActionable | 0.53% | cBioPortal, TCGA Pan-Cancer Atlas |
| KRAS p.G13D | LUAD | DriverHotspotActionable | 0.53% | cBioPortal, TCGA Pan-Cancer Atlas |
| BRAF p.D594N | LUAD | DriverHotspotActionable | 0.35% | cBioPortal, TCGA Pan-Cancer Atlas |
| ERBB2 p.Y772_A775dup | LUAD | DriverHotspotActionable | 0.35% | cBioPortal, TCGA Pan-Cancer Atlas |
| EGFR p.L62R | LUAD | DriverHotspotActionable | 0.35% | cBioPortal, TCGA Pan-Cancer Atlas |
| EGFR p.S768I | LUAD | DriverHotspotActionable | 0.35% | cBioPortal, TCGA Pan-Cancer Atlas |
| EGFR p.T790M | LUAD | DriverHotspotActionable | 0.35% | cBioPortal, TCGA Pan-Cancer Atlas |
| EGFR p.G719A | LUAD | DriverHotspotActionable | 0.35% | cBioPortal, TCGA Pan-Cancer Atlas |
| EGFR p.L747_T751del | LUAD | DriverHotspotActionable | 0.35% | cBioPortal, TCGA Pan-Cancer Atlas |
| BRAF p.G469A | LUAD | DriverHotspotActionable | 0.35% | cBioPortal, TCGA Pan-Cancer Atlas |
| KRAS p.L19F | LUAD | DriverHotspotActionable | 0.35% | cBioPortal, TCGA Pan-Cancer Atlas |
| PIK3CA p.H1047R | LUAD | DriverHotspotActionable | 0.35% | cBioPortal, TCGA Pan-Cancer Atlas |
| EGFR p.L833F | LUAD | DriverHotspotActionable | 0.18% | cBioPortal, TCGA Pan-Cancer Atlas |
| EGFR p.D770_N771insGL | LUAD | DriverHotspotActionable | 0.18% | cBioPortal, TCGA Pan-Cancer Atlas |
| ERBB2 p.S310F | LUAD | DriverHotspotActionable | 0.18% | cBioPortal, TCGA Pan-Cancer Atlas |
| EGFR p.A767_V769dup | LUAD | DriverHotspotActionable | 0.18% | cBioPortal, TCGA Pan-Cancer Atlas |
| EGFR p.G719C | LUAD | DriverHotspotActionable | 0.18% | cBioPortal, TCGA Pan-Cancer Atlas |
| BRAF p.D594H | LUAD | DriverHotspotActionable | 0.18% | cBioPortal, TCGA Pan-Cancer Atlas |
| BRAF p.G596R | LUAD | DriverHotspotActionable | 0.18% | cBioPortal, TCGA Pan-Cancer Atlas |
| EGFR p.K754_I759del | LUAD | DriverHotspotActionable | 0.18% | cBioPortal, TCGA Pan-Cancer Atlas |
| EGFR p.L833V | LUAD | DriverHotspotActionable | 0.18% | cBioPortal, TCGA Pan-Cancer Atlas |
| EGFR p.H773dup | LUAD | DriverHotspotActionable | 0.18% | cBioPortal, TCGA Pan-Cancer Atlas |
| EGFR p.K754E | LUAD | DriverHotspotActionable | 0.18% | cBioPortal, TCGA Pan-Cancer Atlas |