Cancer slice

Prostate Adenocarcinoma (TCGA, PanCancer Atlas)

118 records, 16 actionable signals, and 118 hotspot records in this source-aligned cancer slice.

Variant	Cancer	Evidence	Frequency	Sources
BRAF p.G469A substitution	PRAD	DriverHotspotActionable	0.40%	cBioPortal, TCGA Pan-Cancer Atlas
IDH1 p.R132C substitution	PRAD	DriverHotspotActionable	0.40%	cBioPortal, TCGA Pan-Cancer Atlas
PIK3CA p.E542K substitution	PRAD	DriverHotspotActionable	0.40%	cBioPortal, TCGA Pan-Cancer Atlas
PIK3CA p.H1047R substitution	PRAD	DriverHotspotActionable	0.40%	cBioPortal, TCGA Pan-Cancer Atlas
BRAF p.K601_W604del deletion	PRAD	DriverHotspotActionable	0.20%	cBioPortal, TCGA Pan-Cancer Atlas
ERBB2 p.R678Q substitution	PRAD	DriverHotspotActionable	0.20%	cBioPortal, TCGA Pan-Cancer Atlas
BRAF p.K601E substitution	PRAD	DriverHotspotActionable	0.20%	cBioPortal, TCGA Pan-Cancer Atlas
IDH1 p.R132G substitution	PRAD	DriverHotspotActionable	0.20%	cBioPortal, TCGA Pan-Cancer Atlas
IDH1 p.R132H substitution	PRAD	DriverHotspotActionable	0.20%	cBioPortal, TCGA Pan-Cancer Atlas
KIT p.R888Q substitution	PRAD	DriverHotspotActionable	0.20%	cBioPortal, TCGA Pan-Cancer Atlas
KRAS p.G12R substitution	PRAD	DriverHotspotActionable	0.20%	cBioPortal, TCGA Pan-Cancer Atlas
KRAS p.G12D substitution	PRAD	DriverHotspotActionable	0.20%	cBioPortal, TCGA Pan-Cancer Atlas
PIK3CA p.R88Q substitution	PRAD	DriverHotspotActionable	0.20%	cBioPortal, TCGA Pan-Cancer Atlas
PIK3CA p.N345K substitution	PRAD	DriverHotspotActionable	0.20%	cBioPortal, TCGA Pan-Cancer Atlas
PIK3CA p.E542A substitution	PRAD	DriverHotspotActionable	0.20%	cBioPortal, TCGA Pan-Cancer Atlas
PIK3CA p.R108H substitution	PRAD	DriverHotspotActionable	0.20%	cBioPortal, TCGA Pan-Cancer Atlas
SPOP p.W131G substitution	PRAD	DriverHotspot	1.6%	cBioPortal, TCGA Pan-Cancer Atlas
SPOP p.F133V substitution	PRAD	DriverHotspot	1.2%	cBioPortal, TCGA Pan-Cancer Atlas
SPOP p.F133C substitution	PRAD	DriverHotspot	0.81%	cBioPortal, TCGA Pan-Cancer Atlas
SPOP p.F102V substitution	PRAD	DriverHotspot	0.81%	cBioPortal, TCGA Pan-Cancer Atlas
TP53 p.R248Q substitution	PRAD	DriverHotspot	0.81%	cBioPortal, TCGA Pan-Cancer Atlas
FOXA1 p.F254_N256delinsY deletion	PRAD	DriverHotspot	0.61%	cBioPortal, TCGA Pan-Cancer Atlas
HRAS p.Q61R substitution	PRAD	DriverHotspot	0.61%	cBioPortal, TCGA Pan-Cancer Atlas
TP53 p.G245S substitution	PRAD	DriverHotspot	0.61%	cBioPortal, TCGA Pan-Cancer Atlas
SPOP p.F133L substitution	PRAD	DriverHotspot	0.61%	cBioPortal, TCGA Pan-Cancer Atlas
SPOP p.F133L substitution	PRAD	DriverHotspot	0.61%	cBioPortal, TCGA Pan-Cancer Atlas
AKT1 p.E17K substitution	PRAD	DriverHotspot	0.40%	cBioPortal, TCGA Pan-Cancer Atlas
CTNNB1 p.T41A substitution	PRAD	DriverHotspot	0.40%	cBioPortal, TCGA Pan-Cancer Atlas
CUL3 p.M299R substitution	PRAD	DriverHotspot	0.40%	cBioPortal, TCGA Pan-Cancer Atlas
MED12 p.L1224F substitution	PRAD	DriverHotspot	0.40%	cBioPortal, TCGA Pan-Cancer Atlas
MED12 p.V1223L substitution	PRAD	DriverHotspot	0.40%	cBioPortal, TCGA Pan-Cancer Atlas
SPOP p.Y87S substitution	PRAD	DriverHotspot	0.40%	cBioPortal, TCGA Pan-Cancer Atlas
TP53 p.R175H substitution	PRAD	DriverHotspot	0.40%	cBioPortal, TCGA Pan-Cancer Atlas
TP53 p.R282W substitution	PRAD	DriverHotspot	0.40%	cBioPortal, TCGA Pan-Cancer Atlas
SPOP p.W131R substitution	PRAD	DriverHotspot	0.40%	cBioPortal, TCGA Pan-Cancer Atlas
SPOP p.F102C substitution	PRAD	DriverHotspot	0.40%	cBioPortal, TCGA Pan-Cancer Atlas
SPOP p.Y87C substitution	PRAD	DriverHotspot	0.40%	cBioPortal, TCGA Pan-Cancer Atlas
TP53 p.Y163H substitution	PRAD	DriverHotspot	0.40%	cBioPortal, TCGA Pan-Cancer Atlas
SPOP p.F102S substitution	PRAD	DriverHotspot	0.40%	cBioPortal, TCGA Pan-Cancer Atlas
TP53 p.C141G substitution	PRAD	DriverHotspot	0.40%	cBioPortal, TCGA Pan-Cancer Atlas