Cancer slice

Uveal Melanoma (TCGA, PanCancer Atlas)

122 records, 5 actionable signals, and 22 hotspot records in this source-aligned cancer slice.

Variant	Cancer	Evidence	Frequency	Sources
GNA11 p.Q209L substitution	UM	DriverHotspot	42.5%	cBioPortal, TCGA Pan-Cancer Atlas
GNAQ p.Q209P substitution	UM	DriverHotspot	33.8%	cBioPortal, TCGA Pan-Cancer Atlas
GNAQ p.Q209L substitution	UM	DriverHotspot	12.5%	cBioPortal, TCGA Pan-Cancer Atlas
SF3B1 p.R625H substitution	UM	DriverHotspot	10.0%	cBioPortal, TCGA Pan-Cancer Atlas
SF3B1 p.R625C substitution	UM	DriverHotspot	7.5%	cBioPortal, TCGA Pan-Cancer Atlas
CYSLTR2 p.L129Q substitution	UM	DriverHotspot	3.8%	cBioPortal, TCGA Pan-Cancer Atlas
EIF1AX p.G15D substitution	UM	DriverHotspot	2.5%	cBioPortal, TCGA Pan-Cancer Atlas
EIF1AX p.G6D substitution	UM	DriverHotspot	2.5%	cBioPortal, TCGA Pan-Cancer Atlas
GNAQ p.R183Q substitution	UM	DriverHotspot	2.5%	cBioPortal, TCGA Pan-Cancer Atlas
SF3B1 p.K666T substitution	UM	DriverHotspot	2.5%	cBioPortal, TCGA Pan-Cancer Atlas
EIF1AX p.G9D substitution	UM	DriverHotspot	1.3%	cBioPortal, TCGA Pan-Cancer Atlas
EIF1AX p.G8R substitution	UM	DriverHotspot	1.3%	cBioPortal, TCGA Pan-Cancer Atlas
EIF1AX p.G9R substitution	UM	DriverHotspot	1.3%	cBioPortal, TCGA Pan-Cancer Atlas
EIF1AX p.G8R substitution	UM	DriverHotspot	1.3%	cBioPortal, TCGA Pan-Cancer Atlas
GNAQ p.G48* substitution	UM	DriverHotspot	1.3%	cBioPortal, TCGA Pan-Cancer Atlas
GNAQ p.G48V substitution	UM	DriverHotspot	1.3%	cBioPortal, TCGA Pan-Cancer Atlas
GNA11 p.R183C substitution	UM	DriverHotspot	1.3%	cBioPortal, TCGA Pan-Cancer Atlas
FBXW7 p.R479Q substitution	UM	DriverHotspot	1.3%	cBioPortal, TCGA Pan-Cancer Atlas
SRSF2 p.Y92_H99del deletion	UM	DriverHotspot	1.3%	cBioPortal, TCGA Pan-Cancer Atlas
PPP2R1A p.R183Q substitution	UM	DriverHotspot	1.3%	cBioPortal, TCGA Pan-Cancer Atlas
SRSF2 p.Y92_H100del deletion	UM	DriverHotspot	1.3%	cBioPortal, TCGA Pan-Cancer Atlas
SMARCA4 p.T910M substitution	UM	DriverHotspot	1.3%	cBioPortal, TCGA Pan-Cancer Atlas
BRCA2 p.F2841Kfs*24 frameshift	UM	Likely DriverActionable	1.3%	cBioPortal, TCGA Pan-Cancer Atlas
FGFR2 p.R210* substitution	UM	Likely DriverActionable	1.3%	cBioPortal, TCGA Pan-Cancer Atlas
PDGFRA p.V859M substitution	UM	Likely DriverActionable	1.3%	cBioPortal, TCGA Pan-Cancer Atlas
ROS1 p.P495L substitution	UM	Likely DriverActionable	1.3%	cBioPortal, TCGA Pan-Cancer Atlas
RET p.R177Q substitution	UM	Likely DriverActionable	1.3%	cBioPortal, TCGA Pan-Cancer Atlas
EIF1AX p.W70R substitution	UM	Likely Driver	1.3%	cBioPortal, TCGA Pan-Cancer Atlas
FAT1 p.S1696L substitution	UM	Likely Driver	1.3%	cBioPortal, TCGA Pan-Cancer Atlas
EP300 p.M1962T substitution	UM	Likely Driver	1.3%	cBioPortal, TCGA Pan-Cancer Atlas
BAP1 p.Y223* substitution	UM	Likely Driver	1.3%	cBioPortal, TCGA Pan-Cancer Atlas
ALDH2 p.G316A substitution	UM	Likely Driver	1.3%	cBioPortal, TCGA Pan-Cancer Atlas
CSMD3 p.K36M substitution	UM	Likely Driver	1.3%	cBioPortal, TCGA Pan-Cancer Atlas
BAP1 p.D672Afs*17 frameshift	UM	Likely Driver	1.3%	cBioPortal, TCGA Pan-Cancer Atlas
EWSR1 p.Y86* substitution	UM	Likely Driver	1.3%	cBioPortal, TCGA Pan-Cancer Atlas
BAP1 p.E685V substitution	UM	Likely Driver	1.3%	cBioPortal, TCGA Pan-Cancer Atlas
BCOR p.D718H substitution	UM	Likely Driver	1.3%	cBioPortal, TCGA Pan-Cancer Atlas
CSMD3 p.A843V substitution	UM	Likely Driver	1.3%	cBioPortal, TCGA Pan-Cancer Atlas
BAP1 p.Q441* substitution	UM	Likely Driver	1.3%	cBioPortal, TCGA Pan-Cancer Atlas
BAP1 p.Q40* substitution	UM	Likely Driver	1.3%	cBioPortal, TCGA Pan-Cancer Atlas