Gene dossier

AKT1

34 mutation records across 13 cancer labels and 4 source families.

0 actionable30 hotspotsPI3K-AKT
Top records

Prioritized variant evidence

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VariantCancerEvidenceFrequencySources
AKT1 p.E17K
substitution
BRCADriverHotspot2.3%cBioPortal, TCGA Pan-Cancer Atlas
AKT1 p.E17K
substitution
UCECDriverHotspot1.5%cBioPortal, TCGA Pan-Cancer Atlas
AKT1 p.E17K
substitution
COADREADDriverHotspot0.75%cBioPortal, TCGA Pan-Cancer Atlas
AKT1 p.E17K
substitution
CESCDriverHotspot0.69%cBioPortal, TCGA Pan-Cancer Atlas
AKT1 p.E17K
substitution
THPADriverHotspot0.61%cBioPortal, TCGA Pan-Cancer Atlas
AKT1 p.E17K
substitution
SKCMDriverHotspot0.45%cBioPortal, TCGA Pan-Cancer Atlas
AKT1 p.E17K
substitution
PRADDriverHotspot0.40%cBioPortal, TCGA Pan-Cancer Atlas
AKT1 p.E17K
substitution
LUADDriverHotspot0.35%cBioPortal, TCGA Pan-Cancer Atlas
AKT1 p.D323N
substitution
CESCDriverHotspot0.34%cBioPortal, TCGA Pan-Cancer Atlas
AKT1 p.E17K
substitution
BLCADriverHotspot0.24%cBioPortal, TCGA Pan-Cancer Atlas
AKT1 p.E17K
substitution
STADDriverHotspot0.23%cBioPortal, TCGA Pan-Cancer Atlas
AKT1 p.E17K
substitution
LUSCDriverHotspot0.21%cBioPortal, TCGA Pan-Cancer Atlas
AKT1 p.L52R
substitution
LUSCDriverHotspot0.21%cBioPortal, TCGA Pan-Cancer Atlas
AKT1 p.L52R
substitution
THPADriverHotspot0.20%cBioPortal, TCGA Pan-Cancer Atlas
AKT1 p.D323Y
substitution
PRADDriverHotspot0.20%cBioPortal, TCGA Pan-Cancer Atlas
AKT1 p.E17K
substitution
HNSCDriverHotspot0.19%cBioPortal, TCGA Pan-Cancer Atlas
AKT1 p.Q79K
substitution
UCECDriverHotspot0.19%cBioPortal, TCGA Pan-Cancer Atlas
AKT1 p.L52H
substitution
UCECDriverHotspot0.19%cBioPortal, TCGA Pan-Cancer Atlas
AKT1 p.D323Y
substitution
LUADDriverHotspot0.18%cBioPortal, TCGA Pan-Cancer Atlas
AKT1 p.L52R
substitution
BRCADriverHotspot0.09%cBioPortal, TCGA Pan-Cancer Atlas
AKT1 p.E17*
substitution
Not reportedDriverHotspotNot reportedCancer Hotspots
AKT1 p.E17K
substitution
Not reportedDriverHotspotNot reportedCancer Hotspots
AKT1 p.L52R
substitution
Not reportedDriverHotspotNot reportedCancer Hotspots
AKT1 p.L52H
substitution
Not reportedDriverHotspotNot reportedCancer Hotspots
AKT1 p.Q79K
substitution
Not reportedDriverHotspotNot reportedCancer Hotspots
AKT1 p.D323G
substitution
Not reportedDriverHotspotNot reportedCancer Hotspots
AKT1 p.D323Y
substitution
Not reportedDriverHotspotNot reportedCancer Hotspots
AKT1 p.D323N
substitution
Not reportedDriverHotspotNot reportedCancer Hotspots
AKT1 p.P68_C77dup
inframe
Not reportedDriverHotspotNot reportedCancer Hotspots
AKT1 p.T65_I75dup
inframe
Not reportedDriverHotspotNot reportedCancer Hotspots