Gene dossier

AR

88 mutation records across 4 cancer labels and 4 source families.

0 actionable9 hotspotsNot reported

Top records

Prioritized variant evidence

Variant	Cancer	Evidence	Frequency	Sources
AR p.E308K substitution	CHOL	Likely Driver	2.8%	cBioPortal, TCGA Pan-Cancer Atlas
AR p.A597T substitution	DLBCLNOS	Likely Driver	2.4%	cBioPortal, TCGA Pan-Cancer Atlas
AR p.V758L substitution	DLBCLNOS	Likely Driver	2.4%	cBioPortal, TCGA Pan-Cancer Atlas
AR p.H875Y substitution	COADREAD	DriverHotspot	0.19%	cBioPortal, TCGA Pan-Cancer Atlas
AR p.L702H substitution	COADREAD	DriverHotspot	0.19%	cBioPortal, TCGA Pan-Cancer Atlas
AR p.L702H substitution	Not reported	DriverHotspot	Not reported	Cancer Hotspots
AR p.L702L substitution	Not reported	DriverHotspot	Not reported	Cancer Hotspots
AR p.T878A substitution	Not reported	DriverHotspot	Not reported	Cancer Hotspots
AR p.T878S substitution	Not reported	DriverHotspot	Not reported	Cancer Hotspots
AR p.H875Y substitution	Not reported	DriverHotspot	Not reported	Cancer Hotspots
AR p.W742C substitution	Not reported	DriverHotspot	Not reported	Cancer Hotspots
AR p.W742L substitution	Not reported	DriverHotspot	Not reported	Cancer Hotspots
AR p.Val867Met substitution	UNSPEC	Driver	Not reported	ClinVar
AR p.Val867Met substitution	UNSPEC	Driver	Not reported	ClinVar
AR p.Ser648Asn substitution	UNSPEC	Driver	Not reported	ClinVar
AR p.Ser648Asn substitution	UNSPEC	Driver	Not reported	ClinVar
AR p.Val731Met substitution	UNSPEC	Driver	Not reported	ClinVar
AR p.Val731Met substitution	UNSPEC	Driver	Not reported	ClinVar
AR p.Arg609Lys substitution	UNSPEC	Driver	Not reported	ClinVar
AR p.Arg609Lys substitution	UNSPEC	Driver	Not reported	ClinVar
AR p.Thr878Ala substitution	UNSPEC	Driver	Not reported	ClinVar
AR p.Thr878Ala substitution	UNSPEC	Driver	Not reported	ClinVar
AR p.Thr878Ser substitution	UNSPEC	Driver	Not reported	ClinVar
AR p.Thr878Ser substitution	UNSPEC	Driver	Not reported	ClinVar
AR p.His875Tyr substitution	UNSPEC	Driver	Not reported	ClinVar
AR p.His875Tyr substitution	UNSPEC	Driver	Not reported	ClinVar
AR p.Gln903Arg substitution	UNSPEC	Driver	Not reported	ClinVar
AR p.Gln903Arg substitution	UNSPEC	Driver	Not reported	ClinVar
AR p.Ala722Thr substitution	UNSPEC	VUS	Not reported	ClinVar
AR p.Ala722Thr substitution	UNSPEC	VUS	Not reported	ClinVar