Gene dossier

ATRX

31 mutation records across 10 cancer labels and 4 source families.

0 actionable10 hotspotsNot reported

Top records

Prioritized variant evidence

Variant	Cancer	Evidence	Frequency	Sources
ATRX p.R1504* substitution	DLBCLNOS	Likely Driver	2.4%	cBioPortal, TCGA Pan-Cancer Atlas
ATRX p.N1629D substitution	UCS	Likely Driver	1.8%	cBioPortal, TCGA Pan-Cancer Atlas
ATRX p.R1514Q substitution	UCS	Likely Driver	1.8%	cBioPortal, TCGA Pan-Cancer Atlas
ATRX p.R1698W substitution	UCS	Likely Driver	1.8%	cBioPortal, TCGA Pan-Cancer Atlas
ATRX p.T2205N substitution	UCS	Likely Driver	1.8%	cBioPortal, TCGA Pan-Cancer Atlas
ATRX p.S1124Lfs*6 frameshift	CHRCC	Likely Driver	1.5%	cBioPortal, TCGA Pan-Cancer Atlas
ATRX p.R1426* substitution	DIFG	DriverHotspot	1.2%	cBioPortal, TCGA Pan-Cancer Atlas
ATRX p.P667L substitution	PLMESO	Likely Driver	1.2%	cBioPortal, TCGA Pan-Cancer Atlas
ATRX p.E1365* substitution	ACC	Likely Driver	1.1%	cBioPortal, TCGA Pan-Cancer Atlas
ATRX p.N1754K substitution	ACC	Likely Driver	1.1%	cBioPortal, TCGA Pan-Cancer Atlas
ATRX p.K467* substitution	ACC	Likely Driver	1.1%	cBioPortal, TCGA Pan-Cancer Atlas
ATRX p.Q476* substitution	ACC	Likely Driver	1.1%	cBioPortal, TCGA Pan-Cancer Atlas
ATRX p.F2113Sfs*9 frameshift	DIFG	VUS	0.97%	TCGA Pan-Cancer Atlas, cBioPortal
ATRX p.R781Q substitution	UCEC	VUS	0.97%	cBioPortal, TCGA Pan-Cancer Atlas
ATRX p.R907* substitution	DIFG	DriverHotspot	0.39%	TCGA Pan-Cancer Atlas, cBioPortal
ATRX p.R1426* substitution	UCEC	DriverHotspot	0.39%	cBioPortal, TCGA Pan-Cancer Atlas
ATRX p.R1426* substitution	CESC	DriverHotspot	0.34%	cBioPortal, TCGA Pan-Cancer Atlas
ATRX p.R907* substitution	UCEC	DriverHotspot	0.19%	cBioPortal, TCGA Pan-Cancer Atlas
ATRX p.R1426* substitution	COADREAD	DriverHotspot	0.19%	cBioPortal, TCGA Pan-Cancer Atlas
ATRX p.R1426R substitution	Not reported	DriverHotspot	Not reported	Cancer Hotspots
ATRX p.R1426* substitution	Not reported	DriverHotspot	Not reported	Cancer Hotspots
ATRX p.X199sp inframe	Not reported	DriverHotspot	Not reported	Cancer Hotspots
ATRX p.R907* substitution	Not reported	DriverHotspot	Not reported	Cancer Hotspots
ATRX p.Asn1860Ser substitution	UNSPEC	VUS	Not reported	ClinVar
ATRX p.Asn1860Ser substitution	UNSPEC	VUS	Not reported	ClinVar
ATRX p.Ser576Ter substitution	UNSPEC	Driver	Not reported	ClinVar
ATRX p.Ser576Ter substitution	UNSPEC	Driver	Not reported	ClinVar
ATRX p.Arg2079Ter substitution	UNSPEC	Driver	Not reported	ClinVar
ATRX p.Arg2079Ter substitution	UNSPEC	Driver	Not reported	ClinVar
ATRX p.Arg418Ter substitution	UNSPEC	Driver	Not reported	ClinVar