Gene dossier
CBL
31 mutation records across 2 cancer labels and 4 source families.
0 actionable2 hotspotsNot reported
Top records
Prioritized variant evidence
| Variant | Cancer | Evidence | Frequency | Sources |
|---|---|---|---|---|
| CBL p.V430L | ACC | Likely Driver | 1.1% | cBioPortal, TCGA Pan-Cancer Atlas |
| CBL p.C384R | Not reported | DriverHotspot | Not reported | Cancer Hotspots |
| CBL p.C384W | Not reported | DriverHotspot | Not reported | Cancer Hotspots |
| CBL p.Arg420Gln | UNSPEC | Driver | Not reported | ClinVar |
| CBL p.Arg420Gln | UNSPEC | Driver | Not reported | ClinVar |
| CBL p.Tyr371His | UNSPEC | Driver | Not reported | ClinVar |
| CBL p.Tyr371His | UNSPEC | Driver | Not reported | ClinVar |
| CBL p.Cys384Arg | UNSPEC | Driver | Not reported | ClinVar |
| CBL p.Cys384Arg | UNSPEC | Driver | Not reported | ClinVar |
| CBL p.Cys396Arg | UNSPEC | Driver | Not reported | ClinVar |
| CBL p.Cys396Arg | UNSPEC | Driver | Not reported | ClinVar |
| CBL p.Tyr371Cys | UNSPEC | Driver | Not reported | ClinVar |
| CBL p.Tyr371Cys | UNSPEC | Driver | Not reported | ClinVar |
| CBL c.1096-1G>C | UNSPEC | Driver | Not reported | ClinVar |
| CBL c.1096-1G>C | UNSPEC | Driver | Not reported | ClinVar |
| CBL c.1228-2A>G | UNSPEC | Driver | Not reported | ClinVar |
| CBL c.1228-2A>G | UNSPEC | Driver | Not reported | ClinVar |
| CBL c.1096-1G>T | UNSPEC | Driver | Not reported | ClinVar |
| CBL c.1096-1G>T | UNSPEC | Driver | Not reported | ClinVar |
| CBL p.Tyr371Ser | UNSPEC | Driver | Not reported | ClinVar |
| CBL p.Tyr371Ser | UNSPEC | Driver | Not reported | ClinVar |
| CBL p.Cys401Phe | UNSPEC | VUS | Not reported | ClinVar |
| CBL p.Cys401Phe | UNSPEC | VUS | Not reported | ClinVar |
| CBL c.1096-2A>T | UNSPEC | Driver | Not reported | ClinVar |
| CBL c.1096-2A>T | UNSPEC | Driver | Not reported | ClinVar |
| CBL p.Arg499Ter | UNSPEC | Driver | Not reported | ClinVar |
| CBL p.Arg499Ter | UNSPEC | Driver | Not reported | ClinVar |
| CBL p.His398Arg | UNSPEC | Driver | Not reported | ClinVar |
| CBL p.His398Arg | UNSPEC | Driver | Not reported | ClinVar |
| CBL p.Arg480Gln | UNSPEC | Driver | Not reported | ClinVar |