Gene dossier

CDKN1B

127 mutation records across 2 cancer labels and 4 source families.

0 actionable5 hotspotsNot reported

Top records

Prioritized variant evidence

Variant	Cancer	Evidence	Frequency	Sources
CDKN1B p.G72D substitution	COADREAD	DriverHotspot	0.19%	cBioPortal, TCGA Pan-Cancer Atlas
CDKN1B p.X159sp inframe	Not reported	DriverHotspot	Not reported	Cancer Hotspots
CDKN1B p.G72A substitution	Not reported	DriverHotspot	Not reported	Cancer Hotspots
CDKN1B p.G72D substitution	Not reported	DriverHotspot	Not reported	Cancer Hotspots
CDKN1B p.G72G substitution	Not reported	DriverHotspot	Not reported	Cancer Hotspots
CDKN1B p.Arg43Ter deletion	UNSPEC	Driver	Not reported	ClinVar
CDKN1B p.Arg43Ter deletion	UNSPEC	Driver	Not reported	ClinVar
CDKN1B p.Pro94fs insertion	UNSPEC	Driver	Not reported	ClinVar
CDKN1B p.Pro94fs insertion	UNSPEC	Driver	Not reported	ClinVar
CDKN1B p.Ser112fs deletion	UNSPEC	Driver	Not reported	ClinVar
CDKN1B p.Ser112fs deletion	UNSPEC	Driver	Not reported	ClinVar
CDKN1B p.Pro69Leu substitution	UNSPEC	Driver	Not reported	ClinVar
CDKN1B p.Pro69Leu substitution	UNSPEC	Driver	Not reported	ClinVar
CDKN1B c.-454_-451del deletion	UNSPEC	VUS	Not reported	ClinVar
CDKN1B c.-454_-451del deletion	UNSPEC	VUS	Not reported	ClinVar
CDKN1B p.Asn124_Ser125insTer Microsatellite	UNSPEC	Driver	Not reported	ClinVar
CDKN1B p.Asn124_Ser125insTer Microsatellite	UNSPEC	Driver	Not reported	ClinVar
CDKN1B p.Pro11Ser substitution	UNSPEC	Driver	Not reported	ClinVar
CDKN1B p.Pro11Ser substitution	UNSPEC	Driver	Not reported	ClinVar
CDKN1B p.Lys73fs duplication	UNSPEC	Driver	Not reported	ClinVar
CDKN1B p.Lys73fs duplication	UNSPEC	Driver	Not reported	ClinVar
CDKN1B p.Lys96fs duplication	UNSPEC	Driver	Not reported	ClinVar
CDKN1B p.Lys96fs duplication	UNSPEC	Driver	Not reported	ClinVar
CDKN1B p.Cys148Phe substitution	UNSPEC	Driver	Not reported	ClinVar
CDKN1B p.Cys148Phe substitution	UNSPEC	Driver	Not reported	ClinVar
CDKN1B p.Arg5Ter substitution	UNSPEC	Driver	Not reported	ClinVar
CDKN1B p.Arg5Ter substitution	UNSPEC	Driver	Not reported	ClinVar
CDKN1B p.Asp51fs Microsatellite	UNSPEC	Driver	Not reported	ClinVar
CDKN1B p.Asp51fs Microsatellite	UNSPEC	Driver	Not reported	ClinVar
CDKN1B p.Trp60fs duplication	UNSPEC	Driver	Not reported	ClinVar