Gene dossier
CREBBP
102 mutation records across 17 cancer labels and 4 source families.
0 actionable68 hotspotsChromatin
Top records
Prioritized variant evidence
| Variant | Cancer | Evidence | Frequency | Sources |
|---|---|---|---|---|
| CREBBP p.Y641H | DLBCLNOS | Likely Driver | 2.4% | cBioPortal, TCGA Pan-Cancer Atlas |
| CREBBP p.I1483F | DLBCLNOS | Likely Driver | 2.4% | cBioPortal, TCGA Pan-Cancer Atlas |
| CREBBP p.C1421F | DLBCLNOS | Likely Driver | 2.4% | cBioPortal, TCGA Pan-Cancer Atlas |
| CREBBP p.C1408Y | DLBCLNOS | Likely Driver | 2.4% | cBioPortal, TCGA Pan-Cancer Atlas |
| CREBBP p.S1680del | DLBCLNOS | DriverHotspot | 2.4% | cBioPortal, TCGA Pan-Cancer Atlas |
| CREBBP p.I2101T | UCS | Likely Driver | 1.8% | cBioPortal, TCGA Pan-Cancer Atlas |
| CREBBP p.A206V | UCS | Likely Driver | 1.8% | cBioPortal, TCGA Pan-Cancer Atlas |
| CREBBP p.E1050* | UCS | Likely Driver | 1.8% | cBioPortal, TCGA Pan-Cancer Atlas |
| CREBBP p.R1392Q | UCS | Likely Driver | 1.8% | cBioPortal, TCGA Pan-Cancer Atlas |
| CREBBP p.D1480G | PLMESO | Likely Driver | 1.2% | cBioPortal, TCGA Pan-Cancer Atlas |
| CREBBP p.A341S | ACC | Likely Driver | 1.1% | cBioPortal, TCGA Pan-Cancer Atlas |
| CREBBP p.R1446L | ESCA | DriverHotspot | 0.55% | cBioPortal, TCGA Pan-Cancer Atlas |
| CREBBP p.D1435H | BLCA | DriverHotspot | 0.49% | cBioPortal, TCGA Pan-Cancer Atlas |
| CREBBP p.R1446C | HNSC | DriverHotspot | 0.39% | cBioPortal, TCGA Pan-Cancer Atlas |
| CREBBP p.R1446H | UCEC | DriverHotspot | 0.39% | cBioPortal, TCGA Pan-Cancer Atlas |
| CREBBP p.S1680del | CESC | DriverHotspot | 0.34% | cBioPortal, TCGA Pan-Cancer Atlas |
| CREBBP p.R1446C | CESC | DriverHotspot | 0.34% | cBioPortal, TCGA Pan-Cancer Atlas |
| CREBBP p.R1446H | DIFG | DriverHotspot | 0.25% | cBioPortal, TCGA Pan-Cancer Atlas |
| CREBBP p.D1435Y | BLCA | DriverHotspot | 0.24% | cBioPortal, TCGA Pan-Cancer Atlas |
| CREBBP p.R1446C | BLCA | DriverHotspot | 0.24% | cBioPortal, TCGA Pan-Cancer Atlas |
| CREBBP p.S1680del | BLCA | DriverHotspot | 0.24% | cBioPortal, TCGA Pan-Cancer Atlas |
| CREBBP p.W1502* | BLCA | DriverHotspot | 0.24% | cBioPortal, TCGA Pan-Cancer Atlas |
| CREBBP p.R1446L | BLCA | DriverHotspot | 0.24% | cBioPortal, TCGA Pan-Cancer Atlas |
| CREBBP p.Y1503C | BLCA | DriverHotspot | 0.24% | cBioPortal, TCGA Pan-Cancer Atlas |
| CREBBP p.D1435G | BLCA | DriverHotspot | 0.24% | cBioPortal, TCGA Pan-Cancer Atlas |
| CREBBP p.S1680del | STAD | DriverHotspot | 0.23% | cBioPortal, TCGA Pan-Cancer Atlas |
| CREBBP p.R1446H | STAD | DriverHotspot | 0.23% | cBioPortal, TCGA Pan-Cancer Atlas |
| CREBBP p.R1446C | SKCM | DriverHotspot | 0.23% | cBioPortal, TCGA Pan-Cancer Atlas |
| CREBBP p.Y1450D | LUSC | DriverHotspot | 0.21% | cBioPortal, TCGA Pan-Cancer Atlas |
| CREBBP p.W1472C | LUSC | DriverHotspot | 0.21% | cBioPortal, TCGA Pan-Cancer Atlas |