Gene dossier

CTNNB1

252 mutation records across 15 cancer labels and 4 source families.

0 actionable201 hotspotsWNT

Top records

Prioritized variant evidence

Variant	Cancer	Evidence	Frequency	Sources
CTNNB1 p.S45P substitution	ACC	DriverHotspot	5.5%	cBioPortal, TCGA Pan-Cancer Atlas
CTNNB1 p.S45P substitution	HCC	DriverHotspot	3.0%	cBioPortal, TCGA Pan-Cancer Atlas
CTNNB1 p.S37F substitution	UCEC	DriverHotspot	2.1%	cBioPortal, TCGA Pan-Cancer Atlas
CTNNB1 p.S37C substitution	UCEC	DriverHotspot	1.9%	cBioPortal, TCGA Pan-Cancer Atlas
CTNNB1 p.D32G substitution	HCC	DriverHotspot	1.9%	cBioPortal, TCGA Pan-Cancer Atlas
CTNNB1 p.S33F substitution	UCEC	DriverHotspot	1.7%	cBioPortal, TCGA Pan-Cancer Atlas
CTNNB1 p.S33C substitution	UCEC	DriverHotspot	1.7%	cBioPortal, TCGA Pan-Cancer Atlas
CTNNB1 p.K335I substitution	HCC	DriverHotspot	1.6%	cBioPortal, TCGA Pan-Cancer Atlas
CTNNB1 p.S33C substitution	HCC	DriverHotspot	1.6%	cBioPortal, TCGA Pan-Cancer Atlas
CTNNB1 p.R212H substitution	CHRCC	Likely Driver	1.5%	cBioPortal, TCGA Pan-Cancer Atlas
CTNNB1 p.T41A substitution	HCC	DriverHotspot	1.4%	cBioPortal, TCGA Pan-Cancer Atlas
CTNNB1 p.D32V substitution	HCC	DriverHotspot	1.4%	cBioPortal, TCGA Pan-Cancer Atlas
CTNNB1 p.S33P substitution	HCC	DriverHotspot	1.4%	cBioPortal, TCGA Pan-Cancer Atlas
CTNNB1 p.H36P substitution	HCC	DriverHotspot	1.4%	cBioPortal, TCGA Pan-Cancer Atlas
CTNNB1 p.T41I substitution	UCEC	DriverHotspot	1.4%	cBioPortal, TCGA Pan-Cancer Atlas
CTNNB1 p.D32N substitution	UCEC	DriverHotspot	1.4%	cBioPortal, TCGA Pan-Cancer Atlas
CTNNB1 p.G34R substitution	UCEC	DriverHotspot	1.2%	cBioPortal, TCGA Pan-Cancer Atlas
CTNNB1 p.S33Y substitution	UCEC	DriverHotspot	1.2%	cBioPortal, TCGA Pan-Cancer Atlas
CTNNB1 p.Y30* substitution	ACC	Likely Driver	1.1%	cBioPortal, TCGA Pan-Cancer Atlas
CTNNB1 p.S45F substitution	ACC	DriverHotspot	1.1%	cBioPortal, TCGA Pan-Cancer Atlas
CTNNB1 p.S45del deletion	ACC	DriverHotspot	1.1%	cBioPortal, TCGA Pan-Cancer Atlas
CTNNB1 p.G34R substitution	ACC	DriverHotspot	1.1%	cBioPortal, TCGA Pan-Cancer Atlas
CTNNB1 p.G34V substitution	ACC	DriverHotspot	1.1%	cBioPortal, TCGA Pan-Cancer Atlas
CTNNB1 p.A39Efs*3 frameshift	ACC	Likely Driver	1.1%	cBioPortal, TCGA Pan-Cancer Atlas
CTNNB1 p.S45_P52del deletion	ACC	DriverHotspot	1.1%	cBioPortal, TCGA Pan-Cancer Atlas
CTNNB1 p.T41A substitution	ACC	DriverHotspot	1.1%	cBioPortal, TCGA Pan-Cancer Atlas
CTNNB1 p.G34E substitution	ACC	DriverHotspot	1.1%	cBioPortal, TCGA Pan-Cancer Atlas
CTNNB1 p.S45F substitution	HCC	DriverHotspot	1.1%	cBioPortal, TCGA Pan-Cancer Atlas
CTNNB1 p.D32Y substitution	UCEC	DriverHotspot	0.97%	cBioPortal, TCGA Pan-Cancer Atlas
CTNNB1 p.G34E substitution	UCEC	DriverHotspot	0.97%	cBioPortal, TCGA Pan-Cancer Atlas