Gene dossier
EP300
89 mutation records across 17 cancer labels and 4 source families.
0 actionable48 hotspotsChromatin
Top records
Prioritized variant evidence
| Variant | Cancer | Evidence | Frequency | Sources |
|---|---|---|---|---|
| EP300 p.H41Q | CHOL | Likely Driver | 2.8% | cBioPortal, TCGA Pan-Cancer Atlas |
| EP300 p.S2378N | CHOL | Likely Driver | 2.8% | cBioPortal, TCGA Pan-Cancer Atlas |
| EP300 p.A25P | DLBCLNOS | Likely Driver | 2.4% | cBioPortal, TCGA Pan-Cancer Atlas |
| EP300 p.T1694A | DLBCLNOS | Likely Driver | 2.4% | cBioPortal, TCGA Pan-Cancer Atlas |
| EP300 p.X1429_splice | AML | Likely Driver | 2.0% | cBioPortal, TCGA Pan-Cancer Atlas |
| EP300 p.L18Tfs*21 | UCS | Likely Driver | 1.8% | cBioPortal, TCGA Pan-Cancer Atlas |
| EP300 p.D1399N | CESC | DriverHotspot | 1.4% | cBioPortal, TCGA Pan-Cancer Atlas |
| EP300 p.M1962T | UM | Likely Driver | 1.3% | cBioPortal, TCGA Pan-Cancer Atlas |
| EP300 p.I1185V | PLMESO | Likely Driver | 1.2% | cBioPortal, TCGA Pan-Cancer Atlas |
| EP300 p.F1596del | ACC | Likely Driver | 1.1% | cBioPortal, TCGA Pan-Cancer Atlas |
| EP300 p.D1399N | HNSC | DriverHotspot | 0.97% | cBioPortal, TCGA Pan-Cancer Atlas |
| EP300 p.D1399N | LUSC | DriverHotspot | 0.62% | cBioPortal, TCGA Pan-Cancer Atlas |
| EP300 p.Y1414D | ESCA | DriverHotspot | 0.55% | cBioPortal, TCGA Pan-Cancer Atlas |
| EP300 p.Y1414C | BLCA | DriverHotspot | 0.49% | cBioPortal, TCGA Pan-Cancer Atlas |
| EP300 p.W1466L | STAD | DriverHotspot | 0.46% | cBioPortal, TCGA Pan-Cancer Atlas |
| EP300 p.C1164Y | HNSC | DriverHotspot | 0.39% | cBioPortal, TCGA Pan-Cancer Atlas |
| EP300 p.W1466C | CESC | DriverHotspot | 0.34% | cBioPortal, TCGA Pan-Cancer Atlas |
| EP300 p.C1164Y | BLCA | DriverHotspot | 0.24% | cBioPortal, TCGA Pan-Cancer Atlas |
| EP300 p.D1399Y | BLCA | DriverHotspot | 0.24% | cBioPortal, TCGA Pan-Cancer Atlas |
| EP300 p.Q1455R | BLCA | DriverHotspot | 0.24% | cBioPortal, TCGA Pan-Cancer Atlas |
| EP300 p.Q1455H | BLCA | DriverHotspot | 0.24% | cBioPortal, TCGA Pan-Cancer Atlas |
| EP300 p.Y1414C | LUSC | DriverHotspot | 0.21% | cBioPortal, TCGA Pan-Cancer Atlas |
| EP300 p.W1466C | HNSC | DriverHotspot | 0.19% | cBioPortal, TCGA Pan-Cancer Atlas |
| EP300 p.Y1467S | HNSC | DriverHotspot | 0.19% | cBioPortal, TCGA Pan-Cancer Atlas |
| EP300 p.D1399N | UCEC | DriverHotspot | 0.19% | cBioPortal, TCGA Pan-Cancer Atlas |
| EP300 p.H1451R | UCEC | DriverHotspot | 0.19% | cBioPortal, TCGA Pan-Cancer Atlas |
| EP300 p.D1399N | COADREAD | DriverHotspot | 0.19% | cBioPortal, TCGA Pan-Cancer Atlas |
| EP300 p.H1451P | BRCA | DriverHotspot | 0.09% | cBioPortal, TCGA Pan-Cancer Atlas |
| EP300 p.D1399E | Not reported | DriverHotspot | Not reported | Cancer Hotspots |
| EP300 p.D1399Y | Not reported | DriverHotspot | Not reported | Cancer Hotspots |