Gene dossier

ERBB4

42 mutation records across 9 cancer labels and 3 source families.

0 actionable30 hotspotsNot reported

Top records

Prioritized variant evidence

Variant	Cancer	Evidence	Frequency	Sources
ERBB4 p.S602C substitution	CHOL	Likely Driver	2.8%	cBioPortal, TCGA Pan-Cancer Atlas
ERBB4 p.G627A substitution	DLBCLNOS	Likely Driver	2.4%	cBioPortal, TCGA Pan-Cancer Atlas
ERBB4 p.K1223T substitution	DLBCLNOS	DriverHotspot	2.4%	cBioPortal, TCGA Pan-Cancer Atlas
ERBB4 p.A16V substitution	DLBCLNOS	Likely Driver	2.4%	cBioPortal, TCGA Pan-Cancer Atlas
ERBB4 p.N280T substitution	DLBCLNOS	Likely Driver	2.4%	cBioPortal, TCGA Pan-Cancer Atlas
ERBB4 p.I320V substitution	CHRCC	Likely Driver	1.5%	cBioPortal, TCGA Pan-Cancer Atlas
ERBB4 p.G735C substitution	UM	Likely Driver	1.3%	cBioPortal, TCGA Pan-Cancer Atlas
ERBB4 p.Q45H substitution	PLMESO	Likely Driver	1.2%	cBioPortal, TCGA Pan-Cancer Atlas
ERBB4 p.P224L substitution	ACC	Likely Driver	1.1%	cBioPortal, TCGA Pan-Cancer Atlas
ERBB4 p.E1020V substitution	ACC	Likely Driver	1.1%	cBioPortal, TCGA Pan-Cancer Atlas
ERBB4 p.G130V substitution	ACC	Likely Driver	1.1%	cBioPortal, TCGA Pan-Cancer Atlas
ERBB4 p.V212L substitution	ACC	Likely Driver	1.1%	cBioPortal, TCGA Pan-Cancer Atlas
ERBB4 p.D218G substitution	ACC	Likely Driver	1.1%	cBioPortal, TCGA Pan-Cancer Atlas
ERBB4 p.F1102C substitution	STAD	DriverHotspot	0.46%	cBioPortal, TCGA Pan-Cancer Atlas
ERBB4 p.L798P substitution	BLCA	DriverHotspot	0.24%	cBioPortal, TCGA Pan-Cancer Atlas
ERBB4 p.K1002R substitution	STAD	DriverHotspot	0.23%	cBioPortal, TCGA Pan-Cancer Atlas
ERBB4 p.K1223T substitution	STAD	DriverHotspot	0.23%	cBioPortal, TCGA Pan-Cancer Atlas
ERBB4 p.S774N substitution	STAD	DriverHotspot	0.23%	cBioPortal, TCGA Pan-Cancer Atlas
ERBB4 p.L798P substitution	STAD	DriverHotspot	0.23%	cBioPortal, TCGA Pan-Cancer Atlas
ERBB4 p.K1223M substitution	STAD	DriverHotspot	0.23%	cBioPortal, TCGA Pan-Cancer Atlas
ERBB4 p.S774G substitution	STAD	DriverHotspot	0.23%	cBioPortal, TCGA Pan-Cancer Atlas
ERBB4 p.K1002T substitution	STAD	DriverHotspot	0.23%	cBioPortal, TCGA Pan-Cancer Atlas
ERBB4 p.L798R substitution	STAD	DriverHotspot	0.23%	cBioPortal, TCGA Pan-Cancer Atlas
ERBB4 p.L798H substitution	STAD	DriverHotspot	0.23%	cBioPortal, TCGA Pan-Cancer Atlas
ERBB4 p.K1002T substitution	COADREAD	DriverHotspot	0.19%	cBioPortal, TCGA Pan-Cancer Atlas
ERBB4 p.S1289A substitution	Not reported	DriverHotspot	Not reported	Cancer Hotspots
ERBB4 p.Q707Q substitution	Not reported	DriverHotspot	Not reported	Cancer Hotspots
ERBB4 p.Q707E substitution	Not reported	DriverHotspot	Not reported	Cancer Hotspots
ERBB4 p.L798P substitution	Not reported	DriverHotspot	Not reported	Cancer Hotspots
ERBB4 p.L798R substitution	Not reported	DriverHotspot	Not reported	Cancer Hotspots