Gene dossier

ERCC2

51 mutation records across 6 cancer labels and 4 source families.

0 actionable25 hotspotsNot reported
Top records

Prioritized variant evidence

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VariantCancerEvidenceFrequencySources
ERCC2 p.G675C
substitution
CHOLLikely Driver2.8%cBioPortal, TCGA Pan-Cancer Atlas
ERCC2 p.N238S
substitution
BLCADriverHotspot2.2%cBioPortal, TCGA Pan-Cancer Atlas
ERCC2 p.X635_splice
splice
UMLikely Driver1.3%cBioPortal, TCGA Pan-Cancer Atlas
ERCC2 p.Y72C
substitution
BLCADriverHotspot0.73%cBioPortal, TCGA Pan-Cancer Atlas
ERCC2 p.Y14C
substitution
BLCADriverHotspot0.73%cBioPortal, TCGA Pan-Cancer Atlas
ERCC2 p.E606Q
substitution
BLCADriverHotspot0.49%cBioPortal, TCGA Pan-Cancer Atlas
ERCC2 p.T484A
substitution
HCCDriverHotspot0.27%cBioPortal, TCGA Pan-Cancer Atlas
ERCC2 p.T484M
substitution
BLCADriverHotspot0.24%cBioPortal, TCGA Pan-Cancer Atlas
ERCC2 p.S246Y
substitution
BLCADriverHotspot0.24%cBioPortal, TCGA Pan-Cancer Atlas
ERCC2 p.S246F
substitution
BLCADriverHotspot0.24%cBioPortal, TCGA Pan-Cancer Atlas
ERCC2 p.E606G
substitution
PRADDriverHotspot0.20%cBioPortal, TCGA Pan-Cancer Atlas
ERCC2 p.N238S
substitution
Not reportedDriverHotspotNot reportedCancer Hotspots
ERCC2 p.T484A
substitution
Not reportedDriverHotspotNot reportedCancer Hotspots
ERCC2 p.T484M
substitution
Not reportedDriverHotspotNot reportedCancer Hotspots
ERCC2 p.Y24C
substitution
Not reportedDriverHotspotNot reportedCancer Hotspots
ERCC2 p.Y72C
substitution
Not reportedDriverHotspotNot reportedCancer Hotspots
ERCC2 p.S246S
substitution
Not reportedDriverHotspotNot reportedCancer Hotspots
ERCC2 p.S246F
substitution
Not reportedDriverHotspotNot reportedCancer Hotspots
ERCC2 p.S246Y
substitution
Not reportedDriverHotspotNot reportedCancer Hotspots
ERCC2 p.Y14C
substitution
Not reportedDriverHotspotNot reportedCancer Hotspots
ERCC2 p.P463Q
substitution
Not reportedDriverHotspotNot reportedCancer Hotspots
ERCC2 p.P463S
substitution
Not reportedDriverHotspotNot reportedCancer Hotspots
ERCC2 p.P463L
substitution
Not reportedDriverHotspotNot reportedCancer Hotspots
ERCC2 p.D609E
substitution
Not reportedDriverHotspotNot reportedCancer Hotspots
ERCC2 p.D609G
substitution
Not reportedDriverHotspotNot reportedCancer Hotspots
ERCC2 p.E606Q
substitution
Not reportedDriverHotspotNot reportedCancer Hotspots
ERCC2 p.E606G
substitution
Not reportedDriverHotspotNot reportedCancer Hotspots
ERCC2 p.Arg658Cys
substitution
UNSPECDriverNot reportedClinVar
ERCC2 p.Arg658Cys
substitution
UNSPECDriverNot reportedClinVar
ERCC2 p.Arg683Trp
substitution
UNSPECDriverNot reportedClinVar