Gene dossier

ETV6

35 mutation records across 7 cancer labels and 4 source families.

0 actionable11 hotspotsNot reported

Top records

Prioritized variant evidence

Variant	Cancer	Evidence	Frequency	Sources
ETV6 p.K11N substitution	DLBCLNOS	Likely Driver	2.4%	cBioPortal, TCGA Pan-Cancer Atlas
ETV6 p.X11_splice splice	DLBCLNOS	Likely Driver	2.4%	cBioPortal, TCGA Pan-Cancer Atlas
ETV6 p.X9_splice splice	DLBCLNOS	Likely Driver	2.4%	cBioPortal, TCGA Pan-Cancer Atlas
ETV6 p.I407T substitution	UCS	Likely Driver	1.8%	cBioPortal, TCGA Pan-Cancer Atlas
ETV6 p.S284F substitution	SKCM	DriverHotspot	0.45%	cBioPortal, TCGA Pan-Cancer Atlas
ETV6 p.R369W substitution	COADREAD	DriverHotspot	0.37%	cBioPortal, TCGA Pan-Cancer Atlas
ETV6 p.R369Q substitution	DIFG	DriverHotspot	0.19%	cBioPortal, TCGA Pan-Cancer Atlas
ETV6 p.R369L substitution	LUAD	DriverHotspot	0.18%	cBioPortal, TCGA Pan-Cancer Atlas
ETV6 p.X11sp inframe	Not reported	DriverHotspot	Not reported	Cancer Hotspots
ETV6 p.R369Q substitution	Not reported	DriverHotspot	Not reported	Cancer Hotspots
ETV6 p.R369R substitution	Not reported	DriverHotspot	Not reported	Cancer Hotspots
ETV6 p.R369W substitution	Not reported	DriverHotspot	Not reported	Cancer Hotspots
ETV6 p.R369L substitution	Not reported	DriverHotspot	Not reported	Cancer Hotspots
ETV6 p.S284S substitution	Not reported	DriverHotspot	Not reported	Cancer Hotspots
ETV6 p.S284F substitution	Not reported	DriverHotspot	Not reported	Cancer Hotspots
ETV6 p.Glu76Ter substitution	UNSPEC	Driver	Not reported	ClinVar
ETV6 p.Glu76Ter substitution	UNSPEC	Driver	Not reported	ClinVar
ETV6 p.His436delinsGlnGly insertion	UNSPEC	Driver	Not reported	ClinVar
ETV6 p.His436delinsGlnGly insertion	UNSPEC	Driver	Not reported	ClinVar
ETV6 p.Pro214Leu substitution	UNSPEC	Driver	Not reported	ClinVar
ETV6 p.Pro214Leu substitution	UNSPEC	Driver	Not reported	ClinVar
ETV6 p.Arg369Gln substitution	UNSPEC	Driver	Not reported	ClinVar
ETV6 p.Arg369Gln substitution	UNSPEC	Driver	Not reported	ClinVar
ETV6 p.Arg399Cys substitution	UNSPEC	Driver	Not reported	ClinVar
ETV6 p.Arg399Cys substitution	UNSPEC	Driver	Not reported	ClinVar
ETV6 c.1153-5_1153-1del Microsatellite	UNSPEC	Driver	Not reported	ClinVar
ETV6 c.1153-5_1153-1del Microsatellite	UNSPEC	Driver	Not reported	ClinVar
ETV6 p.Leu349Pro substitution	UNSPEC	Driver	Not reported	ClinVar
ETV6 p.Leu349Pro substitution	UNSPEC	Driver	Not reported	ClinVar
ETV6 p.Arg418Gly substitution	UNSPEC	VUS	Not reported	ClinVar