Gene dossier

FAT1

36 mutation records across 13 cancer labels and 4 source families.

0 actionable8 hotspotsNot reported

Top records

Prioritized variant evidence

Variant	Cancer	Evidence	Frequency	Sources
FAT1 p.P1855L substitution	CHOL	Likely Driver	2.8%	cBioPortal, TCGA Pan-Cancer Atlas
FAT1 p.P2813T substitution	DLBCLNOS	Likely Driver	2.4%	cBioPortal, TCGA Pan-Cancer Atlas
FAT1 p.F360V substitution	DLBCLNOS	Likely Driver	2.4%	cBioPortal, TCGA Pan-Cancer Atlas
FAT1 p.G3272E substitution	DLBCLNOS	Likely Driver	2.4%	cBioPortal, TCGA Pan-Cancer Atlas
FAT1 p.D1802H substitution	DLBCLNOS	Likely Driver	2.4%	cBioPortal, TCGA Pan-Cancer Atlas
FAT1 p.V3758M substitution	DLBCLNOS	Likely Driver	2.4%	cBioPortal, TCGA Pan-Cancer Atlas
FAT1 p.I2605N substitution	DLBCLNOS	Likely Driver	2.4%	cBioPortal, TCGA Pan-Cancer Atlas
FAT1 p.X3357_splice splice	DLBCLNOS	Likely Driver	2.4%	cBioPortal, TCGA Pan-Cancer Atlas
FAT1 p.D2910N substitution	UCS	Likely Driver	1.8%	cBioPortal, TCGA Pan-Cancer Atlas
FAT1 p.R1795* substitution	UCS	Likely Driver	1.8%	cBioPortal, TCGA Pan-Cancer Atlas
FAT1 p.M1149Wfs*55 frameshift	CHRCC	Likely Driver	1.5%	cBioPortal, TCGA Pan-Cancer Atlas
FAT1 p.S1696L substitution	UM	Likely Driver	1.3%	cBioPortal, TCGA Pan-Cancer Atlas
FAT1 p.D2944N substitution	UM	Likely Driver	1.3%	cBioPortal, TCGA Pan-Cancer Atlas
FAT1 p.N3948K substitution	PLMESO	Likely Driver	1.2%	cBioPortal, TCGA Pan-Cancer Atlas
FAT1 p.R2597* substitution	UCEC	Likely Driver	1.2%	cBioPortal, TCGA Pan-Cancer Atlas
FAT1 p.D597Y substitution	ACC	Likely Driver	1.1%	cBioPortal, TCGA Pan-Cancer Atlas
FAT1 p.L3096I substitution	ACC	Likely Driver	1.1%	cBioPortal, TCGA Pan-Cancer Atlas
FAT1 p.T439K substitution	ACC	Likely Driver	1.1%	cBioPortal, TCGA Pan-Cancer Atlas
FAT1 p.R2832M substitution	ACC	Likely Driver	1.1%	cBioPortal, TCGA Pan-Cancer Atlas
FAT1 p.R2832S substitution	ACC	Likely Driver	1.1%	cBioPortal, TCGA Pan-Cancer Atlas
FAT1 p.S2225I substitution	ACC	Likely Driver	1.1%	cBioPortal, TCGA Pan-Cancer Atlas
FAT1 p.D3242G substitution	ACC	Likely Driver	1.1%	cBioPortal, TCGA Pan-Cancer Atlas
FAT1 p.R1627* substitution	UCEC	DriverHotspot	0.58%	cBioPortal, TCGA Pan-Cancer Atlas
FAT1 p.R1627Q substitution	PAAD	DriverHotspot	0.56%	cBioPortal, TCGA Pan-Cancer Atlas
FAT1 p.R1627* substitution	HNSC	DriverHotspot	0.39%	cBioPortal, TCGA Pan-Cancer Atlas
FAT1 p.R1627Q substitution	STAD	DriverHotspot	0.23%	cBioPortal, TCGA Pan-Cancer Atlas
FAT1 p.R1627Q substitution	UCEC	DriverHotspot	0.19%	cBioPortal, TCGA Pan-Cancer Atlas
FAT1 p.R1627Q substitution	COADREAD	DriverHotspot	0.19%	cBioPortal, TCGA Pan-Cancer Atlas
FAT1 p.R1627Q substitution	Not reported	DriverHotspot	Not reported	Cancer Hotspots
FAT1 p.R1627* substitution	Not reported	DriverHotspot	Not reported	Cancer Hotspots