Gene dossier
FLCN
441 mutation records across 3 cancer labels and 3 source families.
0 actionable0 hotspotsNot reported
Top records
Prioritized variant evidence
| Variant | Cancer | Evidence | Frequency | Sources |
|---|---|---|---|---|
| FLCN p.X434_splice | PLMESO | Likely Driver | 1.2% | cBioPortal, TCGA Pan-Cancer Atlas |
| FLCN p.S62R | ACC | Likely Driver | 1.1% | cBioPortal, TCGA Pan-Cancer Atlas |
| FLCN p.His429fs | UNSPEC | Driver | Not reported | ClinVar |
| FLCN p.His429fs | UNSPEC | Driver | Not reported | ClinVar |
| FLCN p.His429fs | UNSPEC | Driver | Not reported | ClinVar |
| FLCN p.His429fs | UNSPEC | Driver | Not reported | ClinVar |
| FLCN p.Tyr463Ter | UNSPEC | Driver | Not reported | ClinVar |
| FLCN p.Tyr463Ter | UNSPEC | Driver | Not reported | ClinVar |
| FLCN p.Ile426fs | UNSPEC | Driver | Not reported | ClinVar |
| FLCN p.Ile426fs | UNSPEC | Driver | Not reported | ClinVar |
| FLCN p.Ser79Trp | UNSPEC | VUS | Not reported | ClinVar |
| FLCN p.Ser79Trp | UNSPEC | VUS | Not reported | ClinVar |
| FLCN p.Ala445Thr | UNSPEC | Driver | Not reported | ClinVar |
| FLCN p.Ala445Thr | UNSPEC | Driver | Not reported | ClinVar |
| FLCN p.Ser79fs | UNSPEC | Driver | Not reported | ClinVar |
| FLCN p.Ser79fs | UNSPEC | Driver | Not reported | ClinVar |
| FLCN p.Glu510_Trp511insTer | UNSPEC | Driver | Not reported | ClinVar |
| FLCN p.Glu510_Trp511insTer | UNSPEC | Driver | Not reported | ClinVar |
| FLCN p.Pro135fs | UNSPEC | Driver | Not reported | ClinVar |
| FLCN p.Pro135fs | UNSPEC | Driver | Not reported | ClinVar |
| FLCN p.Gln373Ter | UNSPEC | Driver | Not reported | ClinVar |
| FLCN p.Gln373Ter | UNSPEC | Driver | Not reported | ClinVar |
| FLCN p.Met394fs | UNSPEC | Driver | Not reported | ClinVar |
| FLCN p.Met394fs | UNSPEC | Driver | Not reported | ClinVar |
| FLCN p.Ile402fs | UNSPEC | Driver | Not reported | ClinVar |
| FLCN p.Ile402fs | UNSPEC | Driver | Not reported | ClinVar |
| FLCN p.Phe435fs | UNSPEC | Driver | Not reported | ClinVar |
| FLCN p.Phe435fs | UNSPEC | Driver | Not reported | ClinVar |
| FLCN c.1433-2A>G | UNSPEC | Driver | Not reported | ClinVar |
| FLCN c.1433-2A>G | UNSPEC | Driver | Not reported | ClinVar |