Gene dossier
HRAS
93 mutation records across 12 cancer labels and 4 source families.
0 actionable65 hotspotsRTK-RAS
Top records
Prioritized variant evidence
| Variant | Cancer | Evidence | Frequency | Sources |
|---|---|---|---|---|
| HRAS p.Q61R | SOFT_TISSUE | DriverHotspot | 7.3% | cBioPortal, TCGA Pan-Cancer Atlas |
| HRAS p.Q61R | THPA | DriverHotspot | 2.7% | cBioPortal, TCGA Pan-Cancer Atlas |
| HRAS p.G13V | THYM | DriverHotspot | 1.6% | cBioPortal, TCGA Pan-Cancer Atlas |
| HRAS p.G13V | HNSC | DriverHotspot | 1.6% | cBioPortal, TCGA Pan-Cancer Atlas |
| HRAS p.G12S | HNSC | DriverHotspot | 1.4% | cBioPortal, TCGA Pan-Cancer Atlas |
| HRAS p.G13R | SOFT_TISSUE | DriverHotspot | 1.1% | cBioPortal, TCGA Pan-Cancer Atlas |
| HRAS p.Q61K | SOFT_TISSUE | DriverHotspot | 1.1% | cBioPortal, TCGA Pan-Cancer Atlas |
| HRAS p.K117R | THYM | DriverHotspot | 0.81% | cBioPortal, TCGA Pan-Cancer Atlas |
| HRAS p.G13R | THYM | DriverHotspot | 0.81% | cBioPortal, TCGA Pan-Cancer Atlas |
| HRAS p.K117N | THYM | DriverHotspot | 0.81% | cBioPortal, TCGA Pan-Cancer Atlas |
| HRAS p.K117N | THYM | DriverHotspot | 0.81% | cBioPortal, TCGA Pan-Cancer Atlas |
| HRAS p.Q61K | BLCA | DriverHotspot | 0.73% | cBioPortal, TCGA Pan-Cancer Atlas |
| HRAS p.Q61K | THPA | DriverHotspot | 0.61% | cBioPortal, TCGA Pan-Cancer Atlas |
| HRAS p.Q61R | PRAD | DriverHotspot | 0.61% | cBioPortal, TCGA Pan-Cancer Atlas |
| HRAS p.G13R | HNSC | DriverHotspot | 0.58% | cBioPortal, TCGA Pan-Cancer Atlas |
| HRAS p.Q61L | HNSC | DriverHotspot | 0.58% | cBioPortal, TCGA Pan-Cancer Atlas |
| HRAS p.G12D | HNSC | DriverHotspot | 0.58% | cBioPortal, TCGA Pan-Cancer Atlas |
| HRAS p.Q61L | SOFT_TISSUE | DriverHotspot | 0.56% | cBioPortal, TCGA Pan-Cancer Atlas |
| HRAS p.G13R | BLCA | DriverHotspot | 0.49% | cBioPortal, TCGA Pan-Cancer Atlas |
| HRAS p.Q61L | BLCA | DriverHotspot | 0.49% | cBioPortal, TCGA Pan-Cancer Atlas |
| HRAS p.G12D | BLCA | DriverHotspot | 0.49% | cBioPortal, TCGA Pan-Cancer Atlas |
| HRAS p.G13D | SKCM | DriverHotspot | 0.45% | cBioPortal, TCGA Pan-Cancer Atlas |
| HRAS p.Q61K | SKCM | DriverHotspot | 0.45% | cBioPortal, TCGA Pan-Cancer Atlas |
| HRAS p.G13C | LUSC | DriverHotspot | 0.41% | cBioPortal, TCGA Pan-Cancer Atlas |
| HRAS p.G13V | LUSC | DriverHotspot | 0.41% | cBioPortal, TCGA Pan-Cancer Atlas |
| HRAS p.G12C | HNSC | DriverHotspot | 0.39% | cBioPortal, TCGA Pan-Cancer Atlas |
| HRAS p.G13D | BLCA | DriverHotspot | 0.24% | cBioPortal, TCGA Pan-Cancer Atlas |
| HRAS p.G12S | BLCA | DriverHotspot | 0.24% | cBioPortal, TCGA Pan-Cancer Atlas |
| HRAS p.G13V | BLCA | DriverHotspot | 0.24% | cBioPortal, TCGA Pan-Cancer Atlas |
| HRAS p.K117N | BLCA | DriverHotspot | 0.24% | cBioPortal, TCGA Pan-Cancer Atlas |