Gene dossier

KDM6A

61 mutation records across 7 cancer labels and 4 source families.

0 actionable15 hotspotsChromatin
Top records

Prioritized variant evidence

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VariantCancerEvidenceFrequencySources
KDM6A p.T1104P
substitution
DLBCLNOSLikely Driver2.4%cBioPortal, TCGA Pan-Cancer Atlas
KDM6A p.Q555*
substitution
BLCADriverHotspot2.2%cBioPortal, TCGA Pan-Cancer Atlas
KDM6A p.S531L
substitution
UCSLikely Driver1.8%cBioPortal, TCGA Pan-Cancer Atlas
KDM6A p.I324V
substitution
UMLikely Driver1.3%cBioPortal, TCGA Pan-Cancer Atlas
KDM6A p.E995K
substitution
PLMESOLikely Driver1.2%cBioPortal, TCGA Pan-Cancer Atlas
KDM6A p.G526E
substitution
PRCCDriverHotspot0.36%cBioPortal, TCGA Pan-Cancer Atlas
KDM6A p.Q1003*
substitution
BLCADriverHotspot0.24%cBioPortal, TCGA Pan-Cancer Atlas
KDM6A p.Q555*
substitution
Not reportedDriverHotspotNot reportedCancer Hotspots
KDM6A p.X1336sp
inframe
Not reportedDriverHotspotNot reportedCancer Hotspots
KDM6A p.X1293sp
inframe
Not reportedDriverHotspotNot reportedCancer Hotspots
KDM6A p.G526E
substitution
Not reportedDriverHotspotNot reportedCancer Hotspots
KDM6A p.G526V
substitution
Not reportedDriverHotspotNot reportedCancer Hotspots
KDM6A p.G526G
substitution
Not reportedDriverHotspotNot reportedCancer Hotspots
KDM6A p.G526*
substitution
Not reportedDriverHotspotNot reportedCancer Hotspots
KDM6A p.X1246sp
inframe
Not reportedDriverHotspotNot reportedCancer Hotspots
KDM6A p.X76sp
inframe
Not reportedDriverHotspotNot reportedCancer Hotspots
KDM6A p.X129sp
inframe
Not reportedDriverHotspotNot reportedCancer Hotspots
KDM6A p.Q1003P
substitution
Not reportedDriverHotspotNot reportedCancer Hotspots
KDM6A p.Q1003*
substitution
Not reportedDriverHotspotNot reportedCancer Hotspots
KDM6A p.Trp251Ter
substitution
UNSPECDriverNot reportedClinVar
KDM6A p.Trp251Ter
substitution
UNSPECDriverNot reportedClinVar
KDM6A c.4161+5_4161+8del
Microsatellite
UNSPECDriverNot reportedClinVar
KDM6A c.4161+5_4161+8del
Microsatellite
UNSPECDriverNot reportedClinVar
KDM6A c.748+1G>A
substitution
UNSPECDriverNot reportedClinVar
KDM6A c.748+1G>A
substitution
UNSPECDriverNot reportedClinVar
KDM6A p.Gln339Ter
substitution
UNSPECDriverNot reportedClinVar
KDM6A p.Gln339Ter
substitution
UNSPECDriverNot reportedClinVar
KDM6A c.2988+1G>A
substitution
UNSPECDriverNot reportedClinVar
KDM6A c.2988+1G>A
substitution
UNSPECDriverNot reportedClinVar
KDM6A c.3094+2T>C
substitution
UNSPECDriverNot reportedClinVar