Gene dossier
MED12
33 mutation records across 13 cancer labels and 4 source families.
0 actionable21 hotspotsNot reported
Top records
Prioritized variant evidence
| Variant | Cancer | Evidence | Frequency | Sources |
|---|---|---|---|---|
| MED12 p.E1251* | CHOL | Likely Driver | 2.8% | cBioPortal, TCGA Pan-Cancer Atlas |
| MED12 p.G391V | DLBCLNOS | Likely Driver | 2.4% | cBioPortal, TCGA Pan-Cancer Atlas |
| MED12 p.R1465H | DLBCLNOS | Likely Driver | 2.4% | cBioPortal, TCGA Pan-Cancer Atlas |
| MED12 p.K1345T | UCS | Likely Driver | 1.8% | cBioPortal, TCGA Pan-Cancer Atlas |
| MED12 p.R590W | UCS | Likely Driver | 1.8% | cBioPortal, TCGA Pan-Cancer Atlas |
| MED12 p.N612T | UCS | Likely Driver | 1.8% | cBioPortal, TCGA Pan-Cancer Atlas |
| MED12 p.D23Y | UCS | Likely Driver | 1.8% | cBioPortal, TCGA Pan-Cancer Atlas |
| MED12 p.P94S | UM | Likely Driver | 1.3% | cBioPortal, TCGA Pan-Cancer Atlas |
| MED12 p.Y1326S | PLMESO | Likely Driver | 1.2% | cBioPortal, TCGA Pan-Cancer Atlas |
| MED12 p.A1447D | ACC | Likely Driver | 1.1% | cBioPortal, TCGA Pan-Cancer Atlas |
| MED12 p.L1224F | PRAD | DriverHotspot | 0.40% | cBioPortal, TCGA Pan-Cancer Atlas |
| MED12 p.V1223L | PRAD | DriverHotspot | 0.40% | cBioPortal, TCGA Pan-Cancer Atlas |
| MED12 p.G44D | SOFT_TISSUE | DriverHotspot | 0.39% | cBioPortal, TCGA Pan-Cancer Atlas |
| MED12 p.L1224F | STAD | DriverHotspot | 0.23% | cBioPortal, TCGA Pan-Cancer Atlas |
| MED12 p.L1224V | LUSC | DriverHotspot | 0.21% | cBioPortal, TCGA Pan-Cancer Atlas |
| MED12 p.G44A | DIFG | DriverHotspot | 0.19% | cBioPortal, TCGA Pan-Cancer Atlas |
| MED12 p.G44C | COADREAD | DriverHotspot | 0.19% | cBioPortal, TCGA Pan-Cancer Atlas |
| MED12 p.G44A | Not reported | DriverHotspot | Not reported | Cancer Hotspots |
| MED12 p.G44S | Not reported | DriverHotspot | Not reported | Cancer Hotspots |
| MED12 p.G44C | Not reported | DriverHotspot | Not reported | Cancer Hotspots |
| MED12 p.G44D | Not reported | DriverHotspot | Not reported | Cancer Hotspots |
| MED12 p.G44V | Not reported | DriverHotspot | Not reported | Cancer Hotspots |
| MED12 p.L1224F | Not reported | DriverHotspot | Not reported | Cancer Hotspots |
| MED12 p.L1224V | Not reported | DriverHotspot | Not reported | Cancer Hotspots |
| MED12 p.V1223V | Not reported | DriverHotspot | Not reported | Cancer Hotspots |
| MED12 p.V1223L | Not reported | DriverHotspot | Not reported | Cancer Hotspots |
| MED12 p.N46_S52del | Not reported | DriverHotspot | Not reported | Cancer Hotspots |
| MED12 p.V41_S52del | Not reported | DriverHotspot | Not reported | Cancer Hotspots |
| MED12 p.G44_F45del | Not reported | DriverHotspot | Not reported | Cancer Hotspots |
| MED12 p.K42_N46del | Not reported | DriverHotspot | Not reported | Cancer Hotspots |