Gene dossier
MET
71 mutation records across 6 cancer labels and 4 source families.
71 actionable27 hotspotsRTK-RAS
Top records
Prioritized variant evidence
| Variant | Cancer | Evidence | Frequency | Sources |
|---|---|---|---|---|
| MET p.M1192I | DLBCLNOS | Likely DriverActionable | 2.4% | cBioPortal, TCGA Pan-Cancer Atlas |
| MET p.K350N | UCS | Likely DriverActionable | 1.8% | cBioPortal, TCGA Pan-Cancer Atlas |
| MET p.E410G | UCS | Likely DriverActionable | 1.8% | cBioPortal, TCGA Pan-Cancer Atlas |
| MET p.M1250T | PRCC | DriverHotspotActionable | 1.4% | cBioPortal, TCGA Pan-Cancer Atlas |
| MET p.V1092I | PRCC | Likely DriverActionable | 1.1% | cBioPortal, TCGA Pan-Cancer Atlas |
| MET p.H1094Y | PRCC | DriverHotspotActionable | 1.1% | cBioPortal, TCGA Pan-Cancer Atlas |
| MET p.F1200I | PRCC | DriverHotspotActionable | 0.72% | cBioPortal, TCGA Pan-Cancer Atlas |
| MET p.Y1230H | PRCC | DriverHotspotActionable | 0.72% | cBioPortal, TCGA Pan-Cancer Atlas |
| MET p.V1070E | PRCC | DriverHotspotActionable | 0.36% | cBioPortal, TCGA Pan-Cancer Atlas |
| MET p.Y1230C | PRCC | DriverHotspotActionable | 0.36% | cBioPortal, TCGA Pan-Cancer Atlas |
| MET p.V1070E | CCRCC | DriverHotspotActionable | 0.25% | cBioPortal, TCGA Pan-Cancer Atlas |
| MET p.Y1003* | LUAD | DriverHotspotActionable | 0.18% | cBioPortal, TCGA Pan-Cancer Atlas |
| MET p.X1010sp | Not reported | DriverHotspotActionable | Not reported | Cancer Hotspots |
| MET p.D1010H | Not reported | DriverHotspotActionable | Not reported | Cancer Hotspots |
| MET p.D1010Y | Not reported | DriverHotspotActionable | Not reported | Cancer Hotspots |
| MET p.D1010N | Not reported | DriverHotspotActionable | Not reported | Cancer Hotspots |
| MET p.V1070A | Not reported | DriverHotspotActionable | Not reported | Cancer Hotspots |
| MET p.V1070R | Not reported | DriverHotspotActionable | Not reported | Cancer Hotspots |
| MET p.V1070E | Not reported | DriverHotspotActionable | Not reported | Cancer Hotspots |
| MET p.M1250T | Not reported | DriverHotspotActionable | Not reported | Cancer Hotspots |
| MET p.F1200V | Not reported | DriverHotspotActionable | Not reported | Cancer Hotspots |
| MET p.F1200I | Not reported | DriverHotspotActionable | Not reported | Cancer Hotspots |
| MET p.Y1230C | Not reported | DriverHotspotActionable | Not reported | Cancer Hotspots |
| MET p.Y1230S | Not reported | DriverHotspotActionable | Not reported | Cancer Hotspots |
| MET p.Y1230H | Not reported | DriverHotspotActionable | Not reported | Cancer Hotspots |
| MET p.H1094R | Not reported | DriverHotspotActionable | Not reported | Cancer Hotspots |
| MET p.H1094Y | Not reported | DriverHotspotActionable | Not reported | Cancer Hotspots |
| MET p.Y1003C | Not reported | DriverHotspotActionable | Not reported | Cancer Hotspots |
| MET p.Y1003F | Not reported | DriverHotspotActionable | Not reported | Cancer Hotspots |
| MET p.Y1003* | Not reported | DriverHotspotActionable | Not reported | Cancer Hotspots |