Gene dossier

MSH2

3,562 mutation records across 1 cancer labels and 2 source families.

0 actionable1 hotspotsDNA Repair
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Prioritized variant evidence

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VariantCancerEvidenceFrequencySources
MSH2 p.E580*
substitution
Not reportedDriverHotspotNot reportedCancer Hotspots
MSH2 p.Pro622Leu
substitution
UNSPECDriverNot reportedClinVar
MSH2 p.Pro622Leu
substitution
UNSPECDriverNot reportedClinVar
MSH2 p.Arg406Ter
substitution
UNSPECDriverNot reportedClinVar
MSH2 p.Arg406Ter
substitution
UNSPECDriverNot reportedClinVar
MSH2 p.His639Tyr
substitution
UNSPECDriverNot reportedClinVar
MSH2 p.His639Tyr
substitution
UNSPECDriverNot reportedClinVar
MSH2 p.Asn596del
deletion
UNSPECDriverNot reportedClinVar
MSH2 p.Asn596del
deletion
UNSPECDriverNot reportedClinVar
MSH2 p.Gln601Ter
substitution
UNSPECDriverNot reportedClinVar
MSH2 p.Gln601Ter
substitution
UNSPECDriverNot reportedClinVar
MSH2 p.Arg524Pro
substitution
UNSPECDriverNot reportedClinVar
MSH2 p.Arg524Pro
substitution
UNSPECDriverNot reportedClinVar
MSH2 p.Val705fs
deletion
UNSPECDriverNot reportedClinVar
MSH2 p.Val705fs
deletion
UNSPECDriverNot reportedClinVar
MSH2 p.Tyr98fs
duplication
UNSPECDriverNot reportedClinVar
MSH2 p.Tyr98fs
duplication
UNSPECDriverNot reportedClinVar
MSH2 p.Ala636Pro
substitution
UNSPECDriverNot reportedClinVar
MSH2 p.Ala636Pro
substitution
UNSPECDriverNot reportedClinVar
MSH2 p.Met152fs
deletion
UNSPECDriverNot reportedClinVar
MSH2 p.Met152fs
deletion
UNSPECDriverNot reportedClinVar
MSH2 p.Gln344Ter
substitution
UNSPECDriverNot reportedClinVar
MSH2 p.Gln344Ter
substitution
UNSPECDriverNot reportedClinVar
MSH2 c.1077-66_1146del
deletion
UNSPECDriverNot reportedClinVar
MSH2 c.1077-66_1146del
deletion
UNSPECDriverNot reportedClinVar
MSH2 p.Glu569fs
deletion
UNSPECDriverNot reportedClinVar
MSH2 p.Glu569fs
deletion
UNSPECDriverNot reportedClinVar
MSH2 p.Arg680Ter
substitution
UNSPECDriverNot reportedClinVar
MSH2 p.Arg680Ter
substitution
UNSPECDriverNot reportedClinVar
MSH2 p.Gln288fs
duplication
UNSPECDriverNot reportedClinVar