Gene dossier

NF2

161 mutation records across 3 cancer labels and 3 source families.

0 actionable0 hotspotsNot reported

Top records

Prioritized variant evidence

Variant	Cancer	Evidence	Frequency	Sources
NF2 p.X333_splice splice	CHOL	Likely Driver	2.8%	cBioPortal, TCGA Pan-Cancer Atlas
NF2 p.R225W substitution	CHOL	Likely Driver	2.8%	cBioPortal, TCGA Pan-Cancer Atlas
NF2 p.R57* substitution	PLMESO	Likely Driver	1.2%	cBioPortal, TCGA Pan-Cancer Atlas
NF2 p.X333_splice splice	PLMESO	Likely Driver	1.2%	cBioPortal, TCGA Pan-Cancer Atlas
NF2 p.W184* substitution	PLMESO	Likely Driver	1.2%	cBioPortal, TCGA Pan-Cancer Atlas
NF2 p.Y144* substitution	PLMESO	Likely Driver	1.2%	cBioPortal, TCGA Pan-Cancer Atlas
NF2 p.K449Rfs*45 frameshift	PLMESO	Likely Driver	1.2%	cBioPortal, TCGA Pan-Cancer Atlas
NF2 p.X39_splice splice	PLMESO	Likely Driver	1.2%	cBioPortal, TCGA Pan-Cancer Atlas
NF2 p.E463* substitution	PLMESO	Likely Driver	1.2%	cBioPortal, TCGA Pan-Cancer Atlas
NF2 p.K413* substitution	PLMESO	Likely Driver	1.2%	cBioPortal, TCGA Pan-Cancer Atlas
NF2 p.S87Gfs*15 frameshift	PLMESO	Likely Driver	1.2%	cBioPortal, TCGA Pan-Cancer Atlas
NF2 p.X447_splice splice	PLMESO	Likely Driver	1.2%	cBioPortal, TCGA Pan-Cancer Atlas
NF2 p.R187Lfs*21 frameshift	PLMESO	Likely Driver	1.2%	cBioPortal, TCGA Pan-Cancer Atlas
NF2 p.Y192* substitution	PLMESO	Likely Driver	1.2%	cBioPortal, TCGA Pan-Cancer Atlas
NF2 p.X121_splice splice	PLMESO	Likely Driver	1.2%	cBioPortal, TCGA Pan-Cancer Atlas
NF2 p.X482_splice splice	PLMESO	Likely Driver	1.2%	cBioPortal, TCGA Pan-Cancer Atlas
NF2 p.X81_splice splice	PLMESO	Likely Driver	1.2%	cBioPortal, TCGA Pan-Cancer Atlas
NF2 p.X226_splice splice	PLMESO	Likely Driver	1.2%	cBioPortal, TCGA Pan-Cancer Atlas
NF2 p.R225fs frameshift	PLMESO	Likely Driver	1.2%	cBioPortal, TCGA Pan-Cancer Atlas
NF2 p.V24* frameshift	PLMESO	Likely Driver	1.2%	cBioPortal, TCGA Pan-Cancer Atlas
NF2 p.Q337* substitution	PLMESO	Likely Driver	1.2%	cBioPortal, TCGA Pan-Cancer Atlas
NF2 p.Y153* frameshift	PLMESO	Likely Driver	1.2%	cBioPortal, TCGA Pan-Cancer Atlas
NF2 p.E465* substitution	PLMESO	Likely Driver	1.2%	cBioPortal, TCGA Pan-Cancer Atlas
NF2 c.240+1G>T substitution	UNSPEC	Driver	Not reported	ClinVar
NF2 c.240+1G>T substitution	UNSPEC	Driver	Not reported	ClinVar
NF2 p.Arg57Ter substitution	UNSPEC	Driver	Not reported	ClinVar
NF2 p.Arg57Ter substitution	UNSPEC	Driver	Not reported	ClinVar
NF2 p.Phe96del Microsatellite	UNSPEC	Driver	Not reported	ClinVar
NF2 p.Phe96del Microsatellite	UNSPEC	Driver	Not reported	ClinVar
NF2 p.Gln320Ter substitution	UNSPEC	Driver	Not reported	ClinVar