Gene dossier
NRAS
113 mutation records across 21 cancer labels and 4 source families.
0 actionable85 hotspotsRTK-RAS
Top records
Prioritized variant evidence
| Variant | Cancer | Evidence | Frequency | Sources |
|---|---|---|---|---|
| NRAS p.Q61R | SKCM | DriverHotspot | 12.3% | cBioPortal, TCGA Pan-Cancer Atlas |
| NRAS p.Q61K | SKCM | DriverHotspot | 8.6% | cBioPortal, TCGA Pan-Cancer Atlas |
| NRAS p.Q61R | THPA | DriverHotspot | 6.3% | cBioPortal, TCGA Pan-Cancer Atlas |
| NRAS p.Q61L | SKCM | DriverHotspot | 3.6% | cBioPortal, TCGA Pan-Cancer Atlas |
| NRAS p.Q61R | CHOL | DriverHotspot | 2.8% | cBioPortal, TCGA Pan-Cancer Atlas |
| NRAS p.G13D | AML | DriverHotspot | 2.5% | cBioPortal, TCGA Pan-Cancer Atlas |
| NRAS p.G12D | AML | DriverHotspot | 2.0% | cBioPortal, TCGA Pan-Cancer Atlas |
| NRAS p.A66V | UCS | Likely Driver | 1.8% | cBioPortal, TCGA Pan-Cancer Atlas |
| NRAS p.Q61K | COADREAD | DriverHotspot | 1.7% | cBioPortal, TCGA Pan-Cancer Atlas |
| NRAS p.Q61K | THPA | DriverHotspot | 1.6% | cBioPortal, TCGA Pan-Cancer Atlas |
| NRAS p.Q61K | CHRCC | DriverHotspot | 1.5% | cBioPortal, TCGA Pan-Cancer Atlas |
| NRAS p.Q61R | TESTIS | DriverHotspot | 1.3% | cBioPortal, TCGA Pan-Cancer Atlas |
| NRAS p.G12D | COADREAD | DriverHotspot | 1.3% | cBioPortal, TCGA Pan-Cancer Atlas |
| NRAS p.M1? | PLMESO | Likely Driver | 1.2% | cBioPortal, TCGA Pan-Cancer Atlas |
| NRAS p.Q61H | AML | DriverHotspot | 1.0% | cBioPortal, TCGA Pan-Cancer Atlas |
| NRAS p.Q61K | AML | DriverHotspot | 1.0% | cBioPortal, TCGA Pan-Cancer Atlas |
| NRAS p.Q61R | UCEC | DriverHotspot | 0.97% | cBioPortal, TCGA Pan-Cancer Atlas |
| NRAS p.Q61K | THYM | DriverHotspot | 0.81% | cBioPortal, TCGA Pan-Cancer Atlas |
| NRAS p.Q61R | THYM | DriverHotspot | 0.81% | cBioPortal, TCGA Pan-Cancer Atlas |
| NRAS p.Q61H | SKCM | DriverHotspot | 0.68% | cBioPortal, TCGA Pan-Cancer Atlas |
| NRAS p.Q61H | SKCM | DriverHotspot | 0.68% | cBioPortal, TCGA Pan-Cancer Atlas |
| NRAS p.G12D | TESTIS | DriverHotspot | 0.67% | cBioPortal, TCGA Pan-Cancer Atlas |
| NRAS p.Q61K | TESTIS | DriverHotspot | 0.67% | cBioPortal, TCGA Pan-Cancer Atlas |
| NRAS p.G12S | TESTIS | DriverHotspot | 0.67% | cBioPortal, TCGA Pan-Cancer Atlas |
| NRAS p.G12D | UCEC | DriverHotspot | 0.58% | cBioPortal, TCGA Pan-Cancer Atlas |
| NRAS p.Q61R | HGSOC | DriverHotspot | 0.57% | cBioPortal, TCGA Pan-Cancer Atlas |
| NRAS p.G12C | COADREAD | DriverHotspot | 0.56% | cBioPortal, TCGA Pan-Cancer Atlas |
| NRAS p.G13R | COADREAD | DriverHotspot | 0.56% | cBioPortal, TCGA Pan-Cancer Atlas |
| NRAS p.Q61R | COADREAD | DriverHotspot | 0.56% | cBioPortal, TCGA Pan-Cancer Atlas |
| NRAS p.Q61L | DIFG | DriverHotspot | 0.50% | cBioPortal, TCGA Pan-Cancer Atlas |