Gene dossier

PALB2

2,878 mutation records across 2 cancer labels and 3 source families.

0 actionable0 hotspotsDNA Repair

Top records

Prioritized variant evidence

Variant	Cancer	Evidence	Frequency	Sources
PALB2 p.G1145S substitution	DLBCLNOS	Likely Driver	2.4%	cBioPortal, TCGA Pan-Cancer Atlas
PALB2 p.Tyr551Ter substitution	UNSPEC	Driver	Not reported	ClinVar
PALB2 p.Tyr551Ter substitution	UNSPEC	Driver	Not reported	ClinVar
PALB2 p.Tyr1183Ter substitution	UNSPEC	Driver	Not reported	ClinVar
PALB2 p.Tyr1183Ter substitution	UNSPEC	Driver	Not reported	ClinVar
PALB2 p.Gln988Ter substitution	UNSPEC	Driver	Not reported	ClinVar
PALB2 p.Gln988Ter substitution	UNSPEC	Driver	Not reported	ClinVar
PALB2 p.Gln343Ter substitution	UNSPEC	Driver	Not reported	ClinVar
PALB2 p.Gln343Ter substitution	UNSPEC	Driver	Not reported	ClinVar
PALB2 ClinVar:126585 deletion	UNSPEC	Driver	Not reported	ClinVar
PALB2 ClinVar:126585\|UNSPEC deletion	UNSPEC	Driver	Not reported	ClinVar
PALB2 p.Thr351fs deletion	UNSPEC	Driver	Not reported	ClinVar
PALB2 p.Thr351fs deletion	UNSPEC	Driver	Not reported	ClinVar
PALB2 p.Lys353fs Microsatellite	UNSPEC	Driver	Not reported	ClinVar
PALB2 p.Lys353fs Microsatellite	UNSPEC	Driver	Not reported	ClinVar
PALB2 p.Phe440fs deletion	UNSPEC	Driver	Not reported	ClinVar
PALB2 p.Phe440fs deletion	UNSPEC	Driver	Not reported	ClinVar
PALB2 p.Phe440fs deletion	UNSPEC	Driver	Not reported	ClinVar
PALB2 p.Phe440fs deletion	UNSPEC	Driver	Not reported	ClinVar
PALB2 p.Thr494fs deletion	UNSPEC	Driver	Not reported	ClinVar
PALB2 p.Thr494fs deletion	UNSPEC	Driver	Not reported	ClinVar
PALB2 p.Leu531fs deletion	UNSPEC	Driver	Not reported	ClinVar
PALB2 p.Leu531fs deletion	UNSPEC	Driver	Not reported	ClinVar
PALB2 p.Glu545Ter substitution	UNSPEC	Driver	Not reported	ClinVar
PALB2 p.Glu545Ter substitution	UNSPEC	Driver	Not reported	ClinVar
PALB2 p.Gln559fs deletion	UNSPEC	Driver	Not reported	ClinVar
PALB2 p.Gln559fs deletion	UNSPEC	Driver	Not reported	ClinVar
PALB2 p.Glu650fs duplication	UNSPEC	Driver	Not reported	ClinVar
PALB2 p.Glu650fs duplication	UNSPEC	Driver	Not reported	ClinVar
PALB2 p.Gln66Ter substitution	UNSPEC	Driver	Not reported	ClinVar