Gene dossier

PAX5

41 mutation records across 5 cancer labels and 4 source families.

0 actionable3 hotspotsNot reported

Top records

Prioritized variant evidence

Variant	Cancer	Evidence	Frequency	Sources
PAX5 p.L185V substitution	DLBCLNOS	Likely Driver	2.4%	cBioPortal, TCGA Pan-Cancer Atlas
PAX5 p.X261_splice splice	DLBCLNOS	Likely Driver	2.4%	cBioPortal, TCGA Pan-Cancer Atlas
PAX5 p.R390H substitution	PLMESO	Likely Driver	1.2%	cBioPortal, TCGA Pan-Cancer Atlas
PAX5 p.X367_splice splice	PLMESO	Likely Driver	1.2%	cBioPortal, TCGA Pan-Cancer Atlas
PAX5 p.V26G substitution	COADREAD	DriverHotspot	0.37%	cBioPortal, TCGA Pan-Cancer Atlas
PAX5 p.V26G substitution	UCEC	DriverHotspot	0.19%	cBioPortal, TCGA Pan-Cancer Atlas
PAX5 p.V26G substitution	Not reported	DriverHotspot	Not reported	Cancer Hotspots
PAX5 p.Pro80Arg substitution	UNSPEC	Driver	Not reported	ClinVar
PAX5 p.Pro80Arg substitution	UNSPEC	Driver	Not reported	ClinVar
PAX5 p.Gly85Arg substitution	UNSPEC	Driver	Not reported	ClinVar
PAX5 p.Gly85Arg substitution	UNSPEC	Driver	Not reported	ClinVar
PAX5 p.Arg221Trp substitution	UNSPEC	Driver	Not reported	ClinVar
PAX5 p.Arg221Trp substitution	UNSPEC	Driver	Not reported	ClinVar
PAX5 p.Arg140Gln substitution	UNSPEC	Driver	Not reported	ClinVar
PAX5 p.Arg140Gln substitution	UNSPEC	Driver	Not reported	ClinVar
PAX5 p.Val26Gly substitution	UNSPEC	Driver	Not reported	ClinVar
PAX5 p.Val26Gly substitution	UNSPEC	Driver	Not reported	ClinVar
PAX5 p.Ser134Cys substitution	UNSPEC	Driver	Not reported	ClinVar
PAX5 p.Ser134Cys substitution	UNSPEC	Driver	Not reported	ClinVar
PAX5 p.Ser357_Trp358insTer deletion	UNSPEC	Driver	Not reported	ClinVar
PAX5 p.Ser357_Trp358insTer deletion	UNSPEC	Driver	Not reported	ClinVar
PAX5 p.Glu205Ter substitution	UNSPEC	Driver	Not reported	ClinVar
PAX5 p.Glu205Ter substitution	UNSPEC	Driver	Not reported	ClinVar
PAX5 p.Asn195fs insertion	UNSPEC	Driver	Not reported	ClinVar
PAX5 p.Asn195fs insertion	UNSPEC	Driver	Not reported	ClinVar
PAX5 c.46+1G>A substitution	UNSPEC	Driver	Not reported	ClinVar
PAX5 c.46+1G>A substitution	UNSPEC	Driver	Not reported	ClinVar
PAX5 p.Trp358Ter substitution	UNSPEC	Driver	Not reported	ClinVar
PAX5 p.Trp358Ter substitution	UNSPEC	Driver	Not reported	ClinVar
PAX5 p.Pro130Thr substitution	UNSPEC	Driver	Not reported	ClinVar