Gene dossier
POLK
42 mutation records across 1 cancer labels and 1 source families.
0 actionable0 hotspotsNot reported
Top records
Prioritized variant evidence
| Variant | Cancer | Evidence | Frequency | Sources |
|---|---|---|---|---|
| POLK c.*66T>C | UNSPEC | Driver | Not reported | ClinVar |
| POLK c.*66T>C | UNSPEC | Driver | Not reported | ClinVar |
| POLK p.Glu29Lys | UNSPEC | Driver | Not reported | ClinVar |
| POLK p.Glu29Lys | UNSPEC | Driver | Not reported | ClinVar |
| POLK p.Ser137Phe | UNSPEC | Driver | Not reported | ClinVar |
| POLK p.Ser137Phe | UNSPEC | Driver | Not reported | ClinVar |
| POLK p.Gly154Glu | UNSPEC | Driver | Not reported | ClinVar |
| POLK p.Gly154Glu | UNSPEC | Driver | Not reported | ClinVar |
| POLK p.Phe155Ser | UNSPEC | Driver | Not reported | ClinVar |
| POLK p.Phe155Ser | UNSPEC | Driver | Not reported | ClinVar |
| POLK p.Phe171Ser | UNSPEC | Driver | Not reported | ClinVar |
| POLK p.Phe171Ser | UNSPEC | Driver | Not reported | ClinVar |
| POLK p.Glu419Gly | UNSPEC | Driver | Not reported | ClinVar |
| POLK p.Glu419Gly | UNSPEC | Driver | Not reported | ClinVar |
| POLK p.Ala428= | UNSPEC | Driver | Not reported | ClinVar |
| POLK p.Ala428= | UNSPEC | Driver | Not reported | ClinVar |
| POLK p.Glu430Gly | UNSPEC | Driver | Not reported | ClinVar |
| POLK p.Glu430Gly | UNSPEC | Driver | Not reported | ClinVar |
| POLK p.Leu442Phe | UNSPEC | Driver | Not reported | ClinVar |
| POLK p.Leu442Phe | UNSPEC | Driver | Not reported | ClinVar |
| POLK p.Gln447= | UNSPEC | Driver | Not reported | ClinVar |
| POLK p.Gln447= | UNSPEC | Driver | Not reported | ClinVar |
| POLK p.Glu449Lys | UNSPEC | Driver | Not reported | ClinVar |
| POLK p.Glu449Lys | UNSPEC | Driver | Not reported | ClinVar |
| POLK p.Lys461Glu | UNSPEC | Driver | Not reported | ClinVar |
| POLK p.Lys461Glu | UNSPEC | Driver | Not reported | ClinVar |
| POLK p.Ile487Thr | UNSPEC | Driver | Not reported | ClinVar |
| POLK p.Ile487Thr | UNSPEC | Driver | Not reported | ClinVar |
| POLK p.Ser528Cys | UNSPEC | Driver | Not reported | ClinVar |
| POLK p.Ser528Cys | UNSPEC | Driver | Not reported | ClinVar |