Gene dossier

RAD50

996 mutation records across 6 cancer labels and 4 source families.

0 actionable5 hotspotsNot reported

Top records

Prioritized variant evidence

Variant	Cancer	Evidence	Frequency	Sources
RAD50 p.N340S substitution	PLMESO	Likely Driver	1.2%	cBioPortal, TCGA Pan-Cancer Atlas
RAD50 p.I1147V substitution	PLMESO	Likely Driver	1.2%	cBioPortal, TCGA Pan-Cancer Atlas
RAD50 p.V892Gfs*5 frameshift	ACC	Likely Driver	1.1%	cBioPortal, TCGA Pan-Cancer Atlas
RAD50 p.S895P substitution	ACC	Likely Driver	1.1%	cBioPortal, TCGA Pan-Cancer Atlas
RAD50 p.D69N substitution	UCEC	DriverHotspot	0.39%	cBioPortal, TCGA Pan-Cancer Atlas
RAD50 p.D69Y substitution	LUAD	DriverHotspot	0.35%	cBioPortal, TCGA Pan-Cancer Atlas
RAD50 p.D69N substitution	BLCA	DriverHotspot	0.24%	cBioPortal, TCGA Pan-Cancer Atlas
RAD50 p.D69Y substitution	Not reported	DriverHotspot	Not reported	Cancer Hotspots
RAD50 p.D69N substitution	Not reported	DriverHotspot	Not reported	Cancer Hotspots
RAD50 p.Arg1093Ter substitution	UNSPEC	Driver	Not reported	ClinVar
RAD50 p.Arg1093Ter substitution	UNSPEC	Driver	Not reported	ClinVar
RAD50 p.Ter1313Tyr substitution	UNSPEC	Driver	Not reported	ClinVar
RAD50 p.Ter1313Tyr substitution	UNSPEC	Driver	Not reported	ClinVar
RAD50 p.Gln941Ter substitution	UNSPEC	Driver	Not reported	ClinVar
RAD50 p.Gln941Ter substitution	UNSPEC	Driver	Not reported	ClinVar
RAD50 p.Glu723fs duplication	UNSPEC	Driver	Not reported	ClinVar
RAD50 p.Glu723fs duplication	UNSPEC	Driver	Not reported	ClinVar
RAD50 p.Gln372Ter substitution	UNSPEC	Driver	Not reported	ClinVar
RAD50 p.Gln372Ter substitution	UNSPEC	Driver	Not reported	ClinVar
RAD50 p.Lys436delinsArgTer Microsatellite	UNSPEC	Driver	Not reported	ClinVar
RAD50 p.Lys436delinsArgTer Microsatellite	UNSPEC	Driver	Not reported	ClinVar
RAD50 p.Gln465Ter substitution	UNSPEC	Driver	Not reported	ClinVar
RAD50 p.Gln465Ter substitution	UNSPEC	Driver	Not reported	ClinVar
RAD50 p.Glu977fs deletion	UNSPEC	Driver	Not reported	ClinVar
RAD50 p.Glu977fs deletion	UNSPEC	Driver	Not reported	ClinVar
RAD50 p.Glu995fs deletion	UNSPEC	Driver	Not reported	ClinVar
RAD50 p.Glu995fs deletion	UNSPEC	Driver	Not reported	ClinVar
RAD50 p.Thr109fs deletion	UNSPEC	Driver	Not reported	ClinVar
RAD50 p.Thr109fs deletion	UNSPEC	Driver	Not reported	ClinVar
RAD50 p.Met1Ile substitution	UNSPEC	Driver	Not reported	ClinVar