Gene dossier
RNF43
44 mutation records across 9 cancer labels and 4 source families.
0 actionable12 hotspotsWNT
Top records
Prioritized variant evidence
| Variant | Cancer | Evidence | Frequency | Sources |
|---|---|---|---|---|
| RNF43 p.G659Vfs*41 | UCEC | Likely Driver | 8.1% | cBioPortal, TCGA Pan-Cancer Atlas |
| RNF43 p.G659Vfs*41 | STAD | Likely Driver | 5.7% | cBioPortal, TCGA Pan-Cancer Atlas |
| RNF43 p.G659Vfs*41 | COADREAD | Likely Driver | 4.3% | cBioPortal, TCGA Pan-Cancer Atlas |
| RNF43 p.P739L | UCS | Likely Driver | 1.8% | cBioPortal, TCGA Pan-Cancer Atlas |
| RNF43 p.G4D | UCS | Likely Driver | 1.8% | cBioPortal, TCGA Pan-Cancer Atlas |
| RNF43 p.N602S | UM | Likely Driver | 1.3% | cBioPortal, TCGA Pan-Cancer Atlas |
| RNF43 p.R609Q | UM | Likely Driver | 1.3% | cBioPortal, TCGA Pan-Cancer Atlas |
| RNF43 p.C451Y | ACC | Likely Driver | 1.1% | cBioPortal, TCGA Pan-Cancer Atlas |
| RNF43 p.R145* | PAAD | DriverHotspot | 0.56% | cBioPortal, TCGA Pan-Cancer Atlas |
| RNF43 p.R371* | ESCA | DriverHotspot | 0.55% | cBioPortal, TCGA Pan-Cancer Atlas |
| RNF43 p.H86R | STAD | DriverHotspot | 0.23% | cBioPortal, TCGA Pan-Cancer Atlas |
| RNF43 p.H86Y | STAD | DriverHotspot | 0.23% | cBioPortal, TCGA Pan-Cancer Atlas |
| RNF43 p.R145* | UCEC | DriverHotspot | 0.19% | cBioPortal, TCGA Pan-Cancer Atlas |
| RNF43 p.R132* | UCEC | DriverHotspot | 0.19% | cBioPortal, TCGA Pan-Cancer Atlas |
| RNF43 p.R145* | COADREAD | DriverHotspot | 0.19% | cBioPortal, TCGA Pan-Cancer Atlas |
| RNF43 p.H86R | Not reported | DriverHotspot | Not reported | Cancer Hotspots |
| RNF43 p.H86Y | Not reported | DriverHotspot | Not reported | Cancer Hotspots |
| RNF43 p.R371* | Not reported | DriverHotspot | Not reported | Cancer Hotspots |
| RNF43 p.R145* | Not reported | DriverHotspot | Not reported | Cancer Hotspots |
| RNF43 p.R132* | Not reported | DriverHotspot | Not reported | Cancer Hotspots |
| RNF43 p.Arg132Ter | UNSPEC | Driver | Not reported | ClinVar |
| RNF43 p.Arg132Ter | UNSPEC | Driver | Not reported | ClinVar |
| RNF43 p.Arg113Ter | UNSPEC | Driver | Not reported | ClinVar |
| RNF43 p.Arg113Ter | UNSPEC | Driver | Not reported | ClinVar |
| RNF43 p.Arg371Ter | UNSPEC | Driver | Not reported | ClinVar |
| RNF43 p.Arg371Ter | UNSPEC | Driver | Not reported | ClinVar |
| RNF43 p.Arg330Ter | UNSPEC | Driver | Not reported | ClinVar |
| RNF43 p.Arg330Ter | UNSPEC | Driver | Not reported | ClinVar |
| RNF43 p.Arg650Ter | UNSPEC | Driver | Not reported | ClinVar |
| RNF43 p.Arg650Ter | UNSPEC | Driver | Not reported | ClinVar |