Gene dossier
SETD2
47 mutation records across 13 cancer labels and 4 source families.
0 actionable19 hotspotsNot reported
Top records
Prioritized variant evidence
| Variant | Cancer | Evidence | Frequency | Sources |
|---|---|---|---|---|
| SETD2 p.L2013Pfs*20 | CHOL | Likely Driver | 2.8% | cBioPortal, TCGA Pan-Cancer Atlas |
| SETD2 p.R2040Q | UCS | Likely Driver | 1.8% | cBioPortal, TCGA Pan-Cancer Atlas |
| SETD2 p.R2399* | CHRCC | Likely Driver | 1.5% | cBioPortal, TCGA Pan-Cancer Atlas |
| SETD2 p.R2040* | UM | Likely Driver | 1.3% | cBioPortal, TCGA Pan-Cancer Atlas |
| SETD2 p.Q1998Rfs*3 | PLMESO | Likely Driver | 1.2% | cBioPortal, TCGA Pan-Cancer Atlas |
| SETD2 p.Q1287* | PLMESO | Likely Driver | 1.2% | cBioPortal, TCGA Pan-Cancer Atlas |
| SETD2 p.V1656F | PLMESO | Likely Driver | 1.2% | cBioPortal, TCGA Pan-Cancer Atlas |
| SETD2 p.T1753Nfs*36 | PLMESO | Likely Driver | 1.2% | cBioPortal, TCGA Pan-Cancer Atlas |
| SETD2 p.Q2142* | PLMESO | Likely Driver | 1.2% | cBioPortal, TCGA Pan-Cancer Atlas |
| SETD2 p.S1251* | PLMESO | Likely Driver | 1.2% | cBioPortal, TCGA Pan-Cancer Atlas |
| SETD2 p.V990G | PLMESO | Likely Driver | 1.2% | cBioPortal, TCGA Pan-Cancer Atlas |
| SETD2 p.Q2239* | PLMESO | Likely Driver | 1.2% | cBioPortal, TCGA Pan-Cancer Atlas |
| SETD2 p.W1460C | ACC | Likely Driver | 1.1% | cBioPortal, TCGA Pan-Cancer Atlas |
| SETD2 p.G1690R | ACC | Likely Driver | 1.1% | cBioPortal, TCGA Pan-Cancer Atlas |
| SETD2 p.Y1666H | CCRCC | DriverHotspot | 0.25% | cBioPortal, TCGA Pan-Cancer Atlas |
| SETD2 p.R1625C | CCRCC | DriverHotspot | 0.25% | cBioPortal, TCGA Pan-Cancer Atlas |
| SETD2 p.R1625H | LUSC | DriverHotspot | 0.21% | cBioPortal, TCGA Pan-Cancer Atlas |
| SETD2 p.H1603R | DIFG | DriverHotspot | 0.19% | cBioPortal, TCGA Pan-Cancer Atlas |
| SETD2 p.R1625C | DIFG | DriverHotspot | 0.19% | cBioPortal, TCGA Pan-Cancer Atlas |
| SETD2 p.H1603R | HNSC | DriverHotspot | 0.19% | cBioPortal, TCGA Pan-Cancer Atlas |
| SETD2 p.R1625C | LUAD | DriverHotspot | 0.18% | cBioPortal, TCGA Pan-Cancer Atlas |
| SETD2 p.R1625H | LUAD | DriverHotspot | 0.18% | cBioPortal, TCGA Pan-Cancer Atlas |
| SETD2 p.R1625L | BRCA | DriverHotspot | 0.09% | cBioPortal, TCGA Pan-Cancer Atlas |
| SETD2 p.R1625C | Not reported | DriverHotspot | Not reported | Cancer Hotspots |
| SETD2 p.R1625S | Not reported | DriverHotspot | Not reported | Cancer Hotspots |
| SETD2 p.R1625H | Not reported | DriverHotspot | Not reported | Cancer Hotspots |
| SETD2 p.R1625L | Not reported | DriverHotspot | Not reported | Cancer Hotspots |
| SETD2 p.Y1666C | Not reported | DriverHotspot | Not reported | Cancer Hotspots |
| SETD2 p.Y1666H | Not reported | DriverHotspot | Not reported | Cancer Hotspots |
| SETD2 p.Y1666* | Not reported | DriverHotspot | Not reported | Cancer Hotspots |