Gene dossier
STK11
517 mutation records across 9 cancer labels and 4 source families.
0 actionable77 hotspotsPI3K-AKT
Top records
Prioritized variant evidence
| Variant | Cancer | Evidence | Frequency | Sources |
|---|---|---|---|---|
| STK11 p.K62Sfs*100 | CHOL | Likely Driver | 2.8% | cBioPortal, TCGA Pan-Cancer Atlas |
| STK11 p.Q220* | ACC | DriverHotspot | 1.1% | cBioPortal, TCGA Pan-Cancer Atlas |
| STK11 p.P179R | ACC | DriverHotspot | 1.1% | cBioPortal, TCGA Pan-Cancer Atlas |
| STK11 p.P221L | ESCA | DriverHotspot | 0.55% | cBioPortal, TCGA Pan-Cancer Atlas |
| STK11 p.Q220* | ESCA | DriverHotspot | 0.55% | cBioPortal, TCGA Pan-Cancer Atlas |
| STK11 p.Q220* | LUAD | DriverHotspot | 0.35% | cBioPortal, TCGA Pan-Cancer Atlas |
| STK11 p.K84* | LUAD | DriverHotspot | 0.35% | cBioPortal, TCGA Pan-Cancer Atlas |
| STK11 p.D194Y | LUAD | DriverHotspot | 0.35% | cBioPortal, TCGA Pan-Cancer Atlas |
| STK11 p.G242W | LUAD | DriverHotspot | 0.35% | cBioPortal, TCGA Pan-Cancer Atlas |
| STK11 p.E223* | LUAD | DriverHotspot | 0.35% | cBioPortal, TCGA Pan-Cancer Atlas |
| STK11 p.W239C | LUAD | DriverHotspot | 0.35% | cBioPortal, TCGA Pan-Cancer Atlas |
| STK11 p.P179Q | CESC | DriverHotspot | 0.34% | cBioPortal, TCGA Pan-Cancer Atlas |
| STK11 p.G251C | SKCM | DriverHotspot | 0.23% | cBioPortal, TCGA Pan-Cancer Atlas |
| STK11 p.G242W | SKCM | DriverHotspot | 0.23% | cBioPortal, TCGA Pan-Cancer Atlas |
| STK11 p.G196V | SKCM | DriverHotspot | 0.23% | cBioPortal, TCGA Pan-Cancer Atlas |
| STK11 p.G251C | THPA | DriverHotspot | 0.20% | cBioPortal, TCGA Pan-Cancer Atlas |
| STK11 p.D194N | HNSC | DriverHotspot | 0.19% | cBioPortal, TCGA Pan-Cancer Atlas |
| STK11 p.G251V | LUAD | DriverHotspot | 0.18% | cBioPortal, TCGA Pan-Cancer Atlas |
| STK11 p.E165* | LUAD | DriverHotspot | 0.18% | cBioPortal, TCGA Pan-Cancer Atlas |
| STK11 p.S216F | LUAD | DriverHotspot | 0.18% | cBioPortal, TCGA Pan-Cancer Atlas |
| STK11 p.G251R | LUAD | DriverHotspot | 0.18% | cBioPortal, TCGA Pan-Cancer Atlas |
| STK11 p.D194H | LUAD | DriverHotspot | 0.18% | cBioPortal, TCGA Pan-Cancer Atlas |
| STK11 p.G251C | LUAD | DriverHotspot | 0.18% | cBioPortal, TCGA Pan-Cancer Atlas |
| STK11 p.G242V | LUAD | DriverHotspot | 0.18% | cBioPortal, TCGA Pan-Cancer Atlas |
| STK11 p.E223V | Not reported | DriverHotspot | Not reported | Cancer Hotspots |
| STK11 p.E223* | Not reported | DriverHotspot | Not reported | Cancer Hotspots |
| STK11 p.E223K | Not reported | DriverHotspot | Not reported | Cancer Hotspots |
| STK11 p.X155sp | Not reported | DriverHotspot | Not reported | Cancer Hotspots |
| STK11 p.X245sp | Not reported | DriverHotspot | Not reported | Cancer Hotspots |
| STK11 p.D194V | Not reported | DriverHotspot | Not reported | Cancer Hotspots |