Pathway slice

Cell Cycle

1,329 records across a visible set of 5genes, ranked by hotspot, driver, source, and actionability signals.

Preparing pathway graph...
Ranked pathway records

Evidence table

VariantCancerEvidenceFrequencySources
CDKN2A p.R80Q
substitution
Not reportedDriverHotspotNot reportedCancer Hotspots
CDKN2A p.R80*
substitution
Not reportedDriverHotspotNot reportedCancer Hotspots
CDKN2A p.H83Q
substitution
Not reportedDriverHotspotNot reportedCancer Hotspots
CDKN2A p.H83R
substitution
Not reportedDriverHotspotNot reportedCancer Hotspots
CDKN2A p.H83D
substitution
Not reportedDriverHotspotNot reportedCancer Hotspots
CDKN2A p.H83Y
substitution
Not reportedDriverHotspotNot reportedCancer Hotspots
CDKN2A p.H83N
substitution
Not reportedDriverHotspotNot reportedCancer Hotspots
CDKN2A p.R58R
substitution
Not reportedDriverHotspotNot reportedCancer Hotspots
CDKN2A p.R58*
substitution
Not reportedDriverHotspotNot reportedCancer Hotspots
CDKN2A p.W110*
substitution
Not reportedDriverHotspotNot reportedCancer Hotspots
CDKN2A p.R80*
substitution
HNSCDriverHotspot4.5%cBioPortal, TCGA Pan-Cancer Atlas
CDKN2A p.P114P
substitution
Not reportedDriverHotspotNot reportedCancer Hotspots
CDKN2A p.P114S
substitution
Not reportedDriverHotspotNot reportedCancer Hotspots
CDKN2A p.P114T
substitution
Not reportedDriverHotspotNot reportedCancer Hotspots
CDKN2A p.P114F
substitution
Not reportedDriverHotspotNot reportedCancer Hotspots
CDKN2A p.P114H
substitution
Not reportedDriverHotspotNot reportedCancer Hotspots
CDKN2A p.P114L
substitution
Not reportedDriverHotspotNot reportedCancer Hotspots
CDKN2A p.D108V
substitution
Not reportedDriverHotspotNot reportedCancer Hotspots
CDKN2A p.D108G
substitution
Not reportedDriverHotspotNot reportedCancer Hotspots
CDKN2A p.D108H
substitution
Not reportedDriverHotspotNot reportedCancer Hotspots
CDKN2A p.D108Y
substitution
Not reportedDriverHotspotNot reportedCancer Hotspots
CDKN2A p.D108N
substitution
Not reportedDriverHotspotNot reportedCancer Hotspots
CDKN2A p.E88E
substitution
Not reportedDriverHotspotNot reportedCancer Hotspots
CDKN2A p.E88*
substitution
Not reportedDriverHotspotNot reportedCancer Hotspots
CDKN2A p.E88K
substitution
Not reportedDriverHotspotNot reportedCancer Hotspots
CDKN2A p.D84A
substitution
Not reportedDriverHotspotNot reportedCancer Hotspots
CDKN2A p.D84D
substitution
Not reportedDriverHotspotNot reportedCancer Hotspots
CDKN2A p.D84V
substitution
Not reportedDriverHotspotNot reportedCancer Hotspots
CDKN2A p.D84G
substitution
Not reportedDriverHotspotNot reportedCancer Hotspots
CDKN2A p.D84Y
substitution
Not reportedDriverHotspotNot reportedCancer Hotspots
CDKN2A p.D84N
substitution
Not reportedDriverHotspotNot reportedCancer Hotspots
CDKN2A p.R58*
substitution
HNSCDriverHotspot2.3%cBioPortal, TCGA Pan-Cancer Atlas
CDK4 p.R24C
substitution
Not reportedDriverHotspotNot reportedCancer Hotspots
CDK4 p.R24S
substitution
Not reportedDriverHotspotNot reportedCancer Hotspots
CDK4 p.R24H
substitution
Not reportedDriverHotspotNot reportedCancer Hotspots
CDK4 p.R24L
substitution
Not reportedDriverHotspotNot reportedCancer Hotspots
CDKN2A p.Q50R
substitution
Not reportedDriverHotspotNot reportedCancer Hotspots
CDKN2A p.Q50H
substitution
Not reportedDriverHotspotNot reportedCancer Hotspots
CDKN2A p.Q50*
substitution
Not reportedDriverHotspotNot reportedCancer Hotspots
CDKN2A p.P114L
substitution
SKCMDriverHotspot2.3%cBioPortal, TCGA Pan-Cancer Atlas