Pathway slice
TP53
12,377 records across a visible set of 5genes, ranked by hotspot, driver, source, and actionability signals.
Preparing pathway graph...
Ranked pathway records
Evidence table
| Variant | Cancer | Evidence | Frequency | Sources |
|---|---|---|---|---|
| TP53 p.R273C | DIFG | DriverHotspot | 10.5% | TCGA Pan-Cancer Atlas, cBioPortal |
| TP53 p.R175H | COADREAD | DriverHotspot | 6.0% | cBioPortal, TCGA Pan-Cancer Atlas |
| TP53 p.R175C | Not reported | DriverHotspot | Not reported | Cancer Hotspots |
| TP53 p.R175G | Not reported | DriverHotspot | Not reported | Cancer Hotspots |
| TP53 p.R175H | Not reported | DriverHotspot | Not reported | Cancer Hotspots |
| TP53 p.R175L | Not reported | DriverHotspot | Not reported | Cancer Hotspots |
| TP53 p.R248P | Not reported | DriverHotspot | Not reported | Cancer Hotspots |
| TP53 p.R248Q | Not reported | DriverHotspot | Not reported | Cancer Hotspots |
| TP53 p.R248R | Not reported | DriverHotspot | Not reported | Cancer Hotspots |
| TP53 p.R248W | Not reported | DriverHotspot | Not reported | Cancer Hotspots |
| TP53 p.R248G | Not reported | DriverHotspot | Not reported | Cancer Hotspots |
| TP53 p.R248L | Not reported | DriverHotspot | Not reported | Cancer Hotspots |
| TP53 p.R273P | Not reported | DriverHotspot | Not reported | Cancer Hotspots |
| TP53 p.R273C | Not reported | DriverHotspot | Not reported | Cancer Hotspots |
| TP53 p.R273S | Not reported | DriverHotspot | Not reported | Cancer Hotspots |
| TP53 p.R273G | Not reported | DriverHotspot | Not reported | Cancer Hotspots |
| TP53 p.R273H | Not reported | DriverHotspot | Not reported | Cancer Hotspots |
| TP53 p.R273L | Not reported | DriverHotspot | Not reported | Cancer Hotspots |
| TP53 p.Y220C | Not reported | DriverHotspot | Not reported | Cancer Hotspots |
| TP53 p.Y220S | Not reported | DriverHotspot | Not reported | Cancer Hotspots |
| TP53 p.Y220D | Not reported | DriverHotspot | Not reported | Cancer Hotspots |
| TP53 p.Y220H | Not reported | DriverHotspot | Not reported | Cancer Hotspots |
| TP53 p.Y220* | Not reported | DriverHotspot | Not reported | Cancer Hotspots |
| TP53 p.Y220N | Not reported | DriverHotspot | Not reported | Cancer Hotspots |
| TP53 p.G245A | Not reported | DriverHotspot | Not reported | Cancer Hotspots |
| TP53 p.G245R | Not reported | DriverHotspot | Not reported | Cancer Hotspots |
| TP53 p.G245S | Not reported | DriverHotspot | Not reported | Cancer Hotspots |
| TP53 p.G245C | Not reported | DriverHotspot | Not reported | Cancer Hotspots |
| TP53 p.G245D | Not reported | DriverHotspot | Not reported | Cancer Hotspots |
| TP53 p.G245V | Not reported | DriverHotspot | Not reported | Cancer Hotspots |
| TP53 p.G245N | Not reported | DriverHotspot | Not reported | Cancer Hotspots |
| TP53 p.R213P | Not reported | DriverHotspot | Not reported | Cancer Hotspots |
| TP53 p.R213Q | Not reported | DriverHotspot | Not reported | Cancer Hotspots |
| TP53 p.R213G | Not reported | DriverHotspot | Not reported | Cancer Hotspots |
| TP53 p.R213* | Not reported | DriverHotspot | Not reported | Cancer Hotspots |
| TP53 p.R213L | Not reported | DriverHotspot | Not reported | Cancer Hotspots |
| TP53 p.R282P | Not reported | DriverHotspot | Not reported | Cancer Hotspots |
| TP53 p.R282Q | Not reported | DriverHotspot | Not reported | Cancer Hotspots |
| TP53 p.R282R | Not reported | DriverHotspot | Not reported | Cancer Hotspots |
| TP53 p.R282W | Not reported | DriverHotspot | Not reported | Cancer Hotspots |