Pathway slice

WNT

2,710 records across a visible set of 3genes, ranked by hotspot, driver, source, and actionability signals.

Preparing pathway graph...
Ranked pathway records

Evidence table

VariantCancerEvidenceFrequencySources
CTNNB1 p.S37P
substitution
Not reportedDriverHotspotNot reportedCancer Hotspots
CTNNB1 p.S37A
substitution
Not reportedDriverHotspotNot reportedCancer Hotspots
CTNNB1 p.S37C
substitution
Not reportedDriverHotspotNot reportedCancer Hotspots
CTNNB1 p.S37F
substitution
Not reportedDriverHotspotNot reportedCancer Hotspots
CTNNB1 p.S37Y
substitution
Not reportedDriverHotspotNot reportedCancer Hotspots
CTNNB1 p.D32A
substitution
Not reportedDriverHotspotNot reportedCancer Hotspots
CTNNB1 p.D32V
substitution
Not reportedDriverHotspotNot reportedCancer Hotspots
CTNNB1 p.D32G
substitution
Not reportedDriverHotspotNot reportedCancer Hotspots
CTNNB1 p.D32H
substitution
Not reportedDriverHotspotNot reportedCancer Hotspots
CTNNB1 p.D32Y
substitution
Not reportedDriverHotspotNot reportedCancer Hotspots
CTNNB1 p.D32N
substitution
Not reportedDriverHotspotNot reportedCancer Hotspots
CTNNB1 p.S33P
substitution
Not reportedDriverHotspotNot reportedCancer Hotspots
CTNNB1 p.S33A
substitution
Not reportedDriverHotspotNot reportedCancer Hotspots
CTNNB1 p.S33C
substitution
Not reportedDriverHotspotNot reportedCancer Hotspots
CTNNB1 p.S33T
substitution
Not reportedDriverHotspotNot reportedCancer Hotspots
CTNNB1 p.S33F
substitution
Not reportedDriverHotspotNot reportedCancer Hotspots
CTNNB1 p.S33Y
substitution
Not reportedDriverHotspotNot reportedCancer Hotspots
CTNNB1 p.T41A
substitution
Not reportedDriverHotspotNot reportedCancer Hotspots
CTNNB1 p.T41I
substitution
Not reportedDriverHotspotNot reportedCancer Hotspots
CTNNB1 p.T41N
substitution
Not reportedDriverHotspotNot reportedCancer Hotspots
CTNNB1 p.S45P
substitution
Not reportedDriverHotspotNot reportedCancer Hotspots
CTNNB1 p.S45A
substitution
Not reportedDriverHotspotNot reportedCancer Hotspots
CTNNB1 p.S45C
substitution
Not reportedDriverHotspotNot reportedCancer Hotspots
CTNNB1 p.S45F
substitution
Not reportedDriverHotspotNot reportedCancer Hotspots
CTNNB1 p.S45Y
substitution
Not reportedDriverHotspotNot reportedCancer Hotspots
CTNNB1 p.G34A
substitution
Not reportedDriverHotspotNot reportedCancer Hotspots
CTNNB1 p.G34R
substitution
Not reportedDriverHotspotNot reportedCancer Hotspots
CTNNB1 p.G34E
substitution
Not reportedDriverHotspotNot reportedCancer Hotspots
CTNNB1 p.G34V
substitution
Not reportedDriverHotspotNot reportedCancer Hotspots
CTNNB1 p.G34*
substitution
Not reportedDriverHotspotNot reportedCancer Hotspots
CTNNB1 p.G34L
substitution
Not reportedDriverHotspotNot reportedCancer Hotspots
APC p.R213*
substitution
Not reportedDriverHotspotNot reportedCancer Hotspots
APC p.R213*
substitution
COADREADDriverHotspot3.4%cBioPortal, TCGA Pan-Cancer Atlas
APC p.Q1367E
substitution
Not reportedDriverHotspotNot reportedCancer Hotspots
APC p.Q1367*
substitution
Not reportedDriverHotspotNot reportedCancer Hotspots
CTNNB1 p.S23_S33del
inframe
Not reportedDriverHotspotNot reportedCancer Hotspots
CTNNB1 p.T41_S47del
inframe
Not reportedDriverHotspotNot reportedCancer Hotspots
CTNNB1 p.S33_A39del
inframe
Not reportedDriverHotspotNot reportedCancer Hotspots
CTNNB1 p.S45_P52del
inframe
Not reportedDriverHotspotNot reportedCancer Hotspots
CTNNB1 p.W25_H36del
inframe
Not reportedDriverHotspotNot reportedCancer Hotspots