Cancer slice

Cholangiocarcinoma (TCGA, PanCancer Atlas)

208 records, 18 actionable signals, and 24 hotspot records in this source-aligned cancer slice.

Variant	Cancer	Evidence	Frequency	Sources
IDH1 p.R132C substitution	CHOL	DriverHotspotActionable	11.1%	cBioPortal, TCGA Pan-Cancer Atlas
ERBB2 p.L755S substitution	CHOL	DriverHotspotActionable	2.8%	cBioPortal, TCGA Pan-Cancer Atlas
BRAF p.V600E substitution	CHOL	DriverHotspotActionable	2.8%	cBioPortal, TCGA Pan-Cancer Atlas
IDH2 p.R172S substitution	CHOL	DriverHotspotActionable	2.8%	cBioPortal, TCGA Pan-Cancer Atlas
KRAS p.G12R substitution	CHOL	DriverHotspotActionable	2.8%	cBioPortal, TCGA Pan-Cancer Atlas
FGFR2 p.F276C substitution	CHOL	DriverHotspotActionable	2.8%	cBioPortal, TCGA Pan-Cancer Atlas
FGFR2 p.Y375C substitution	CHOL	DriverHotspotActionable	2.8%	cBioPortal, TCGA Pan-Cancer Atlas
IDH1 p.R132S substitution	CHOL	DriverHotspotActionable	2.8%	cBioPortal, TCGA Pan-Cancer Atlas
IDH2 p.R172K substitution	CHOL	DriverHotspotActionable	2.8%	cBioPortal, TCGA Pan-Cancer Atlas
KRAS p.Q61K substitution	CHOL	DriverHotspotActionable	2.8%	cBioPortal, TCGA Pan-Cancer Atlas
PIK3CA p.H1047L substitution	CHOL	DriverHotspotActionable	2.8%	cBioPortal, TCGA Pan-Cancer Atlas
PIK3CA p.E545K substitution	CHOL	DriverHotspotActionable	2.8%	cBioPortal, TCGA Pan-Cancer Atlas
ARAF p.P216L substitution	CHOL	DriverHotspot	5.6%	cBioPortal, TCGA Pan-Cancer Atlas
DICER1 p.S1344L substitution	CHOL	DriverHotspot	2.8%	cBioPortal, TCGA Pan-Cancer Atlas
CDKN2A p.D84Y substitution	CHOL	DriverHotspot	2.8%	cBioPortal, TCGA Pan-Cancer Atlas
MAP2K1 p.G128R substitution	CHOL	DriverHotspot	2.8%	cBioPortal, TCGA Pan-Cancer Atlas
NRAS p.Q61R substitution	CHOL	DriverHotspot	2.8%	cBioPortal, TCGA Pan-Cancer Atlas
NFE2L2 p.E82D substitution	CHOL	DriverHotspot	2.8%	cBioPortal, TCGA Pan-Cancer Atlas
TP53 p.R248W substitution	CHOL	DriverHotspot	2.8%	cBioPortal, TCGA Pan-Cancer Atlas
TP53 p.S241F substitution	CHOL	DriverHotspot	2.8%	cBioPortal, TCGA Pan-Cancer Atlas
TP53 p.C141R substitution	CHOL	DriverHotspot	2.8%	cBioPortal, TCGA Pan-Cancer Atlas
TP53 p.Y234* substitution	CHOL	DriverHotspot	2.8%	cBioPortal, TCGA Pan-Cancer Atlas
SF3B1 p.G740E substitution	CHOL	DriverHotspot	2.8%	cBioPortal, TCGA Pan-Cancer Atlas
PTEN p.L320* frameshift	CHOL	DriverHotspot	2.8%	cBioPortal, TCGA Pan-Cancer Atlas
BRCA2 p.E1514Q substitution	CHOL	Likely DriverActionable	2.8%	cBioPortal, TCGA Pan-Cancer Atlas
ERBB2 p.L994V substitution	CHOL	Likely DriverActionable	2.8%	cBioPortal, TCGA Pan-Cancer Atlas
NTRK3 p.G374A substitution	CHOL	Likely DriverActionable	2.8%	cBioPortal, TCGA Pan-Cancer Atlas
FLT3 p.R849H substitution	CHOL	Likely DriverActionable	2.8%	cBioPortal, TCGA Pan-Cancer Atlas
RET p.A294V substitution	CHOL	Likely DriverActionable	2.8%	cBioPortal, TCGA Pan-Cancer Atlas
ROS1 p.P1545S substitution	CHOL	Likely DriverActionable	2.8%	cBioPortal, TCGA Pan-Cancer Atlas
BCOR p.P326T substitution	CHOL	Likely Driver	5.6%	cBioPortal, TCGA Pan-Cancer Atlas
CSF1R p.X399_splice splice	CHOL	Likely Driver	2.8%	cBioPortal, TCGA Pan-Cancer Atlas
EZH2 p.H282N substitution	CHOL	Likely Driver	2.8%	cBioPortal, TCGA Pan-Cancer Atlas
EPHA2 p.N674I substitution	CHOL	Likely Driver	2.8%	cBioPortal, TCGA Pan-Cancer Atlas
COL6A3 p.I362V substitution	CHOL	Likely Driver	2.8%	cBioPortal, TCGA Pan-Cancer Atlas
AFDN p.K312R substitution	CHOL	Likely Driver	2.8%	cBioPortal, TCGA Pan-Cancer Atlas
CDKN2A p.E119Q substitution	CHOL	Likely Driver	2.8%	cBioPortal, TCGA Pan-Cancer Atlas
BAP1 p.E454Sfs*117 frameshift	CHOL	Likely Driver	2.8%	cBioPortal, TCGA Pan-Cancer Atlas
BIRC6 p.R2943G substitution	CHOL	Likely Driver	2.8%	cBioPortal, TCGA Pan-Cancer Atlas
ELF3 p.S20Hfs*15 frameshift	CHOL	Likely Driver	2.8%	cBioPortal, TCGA Pan-Cancer Atlas