Cancer slice

Stomach Adenocarcinoma (TCGA, PanCancer Atlas)

328 records, 53 actionable signals, and 300 hotspot records in this source-aligned cancer slice.

Variant	Cancer	Evidence	Frequency	Sources
PIK3CA p.H1047R substitution	STAD	DriverHotspotActionable	3.7%	cBioPortal, TCGA Pan-Cancer Atlas
KRAS p.G13D substitution	STAD	DriverHotspotActionable	2.5%	cBioPortal, TCGA Pan-Cancer Atlas
KRAS p.G12D substitution	STAD	DriverHotspotActionable	2.3%	cBioPortal, TCGA Pan-Cancer Atlas
PIK3CA p.E545K substitution	STAD	DriverHotspotActionable	2.3%	cBioPortal, TCGA Pan-Cancer Atlas
PIK3CA p.E542K substitution	STAD	DriverHotspotActionable	1.4%	cBioPortal, TCGA Pan-Cancer Atlas
PIK3CA p.R88Q substitution	STAD	DriverHotspotActionable	1.4%	cBioPortal, TCGA Pan-Cancer Atlas
ERBB2 p.S310F substitution	STAD	DriverHotspotActionable	1.1%	cBioPortal, TCGA Pan-Cancer Atlas
PIK3CA p.N345K substitution	STAD	DriverHotspotActionable	1.1%	cBioPortal, TCGA Pan-Cancer Atlas
ERBB2 p.R678Q substitution	STAD	DriverHotspotActionable	0.92%	cBioPortal, TCGA Pan-Cancer Atlas
KRAS p.G12S substitution	STAD	DriverHotspotActionable	0.92%	cBioPortal, TCGA Pan-Cancer Atlas
KRAS p.A146T substitution	STAD	DriverHotspotActionable	0.69%	cBioPortal, TCGA Pan-Cancer Atlas
KRAS p.G12V substitution	STAD	DriverHotspotActionable	0.69%	cBioPortal, TCGA Pan-Cancer Atlas
KRAS p.A59T substitution	STAD	DriverHotspotActionable	0.69%	cBioPortal, TCGA Pan-Cancer Atlas
PIK3CA p.C420R substitution	STAD	DriverHotspotActionable	0.69%	cBioPortal, TCGA Pan-Cancer Atlas
PIK3CA p.E453K substitution	STAD	DriverHotspotActionable	0.69%	cBioPortal, TCGA Pan-Cancer Atlas
PIK3CA p.R93Q substitution	STAD	DriverHotspotActionable	0.69%	cBioPortal, TCGA Pan-Cancer Atlas
EGFR p.R252H substitution	STAD	DriverHotspotActionable	0.46%	cBioPortal, TCGA Pan-Cancer Atlas
KRAS p.G12C substitution	STAD	DriverHotspotActionable	0.46%	cBioPortal, TCGA Pan-Cancer Atlas
KRAS p.Q61H substitution	STAD	DriverHotspotActionable	0.46%	cBioPortal, TCGA Pan-Cancer Atlas
PIK3CA p.R38H substitution	STAD	DriverHotspotActionable	0.46%	cBioPortal, TCGA Pan-Cancer Atlas
PIK3CA p.Q546R substitution	STAD	DriverHotspotActionable	0.46%	cBioPortal, TCGA Pan-Cancer Atlas
PIK3CA p.G118D substitution	STAD	DriverHotspotActionable	0.46%	cBioPortal, TCGA Pan-Cancer Atlas
PIK3CA p.K111E substitution	STAD	DriverHotspotActionable	0.46%	cBioPortal, TCGA Pan-Cancer Atlas
ERBB2 p.V777M substitution	STAD	DriverHotspotActionable	0.23%	cBioPortal, TCGA Pan-Cancer Atlas
BRAF p.K601T substitution	STAD	DriverHotspotActionable	0.23%	cBioPortal, TCGA Pan-Cancer Atlas
BRAF p.K601E substitution	STAD	DriverHotspotActionable	0.23%	cBioPortal, TCGA Pan-Cancer Atlas
ERBB2 p.T862A substitution	STAD	DriverHotspotActionable	0.23%	cBioPortal, TCGA Pan-Cancer Atlas
ERBB2 p.V659D substitution	STAD	DriverHotspotActionable	0.23%	cBioPortal, TCGA Pan-Cancer Atlas
ERBB2 p.D769Y substitution	STAD	DriverHotspotActionable	0.23%	cBioPortal, TCGA Pan-Cancer Atlas
ERBB2 p.V842I substitution	STAD	DriverHotspotActionable	0.23%	cBioPortal, TCGA Pan-Cancer Atlas
ERBB2 p.G776V substitution	STAD	DriverHotspotActionable	0.23%	cBioPortal, TCGA Pan-Cancer Atlas
ERBB2 p.S310Y substitution	STAD	DriverHotspotActionable	0.23%	cBioPortal, TCGA Pan-Cancer Atlas
ERBB2 p.L755S substitution	STAD	DriverHotspotActionable	0.23%	cBioPortal, TCGA Pan-Cancer Atlas
BRAF p.G469A substitution	STAD	DriverHotspotActionable	0.23%	cBioPortal, TCGA Pan-Cancer Atlas
KIT p.K642N substitution	STAD	DriverHotspotActionable	0.23%	cBioPortal, TCGA Pan-Cancer Atlas
FGFR3 p.G380R substitution	STAD	DriverHotspotActionable	0.23%	cBioPortal, TCGA Pan-Cancer Atlas
FGFR2 p.C382R substitution	STAD	DriverHotspotActionable	0.23%	cBioPortal, TCGA Pan-Cancer Atlas
PIK3CA p.Y1021C substitution	STAD	DriverHotspotActionable	0.23%	cBioPortal, TCGA Pan-Cancer Atlas
PIK3CA p.E545G substitution	STAD	DriverHotspotActionable	0.23%	cBioPortal, TCGA Pan-Cancer Atlas
PIK3CA p.H1047Y substitution	STAD	DriverHotspotActionable	0.23%	cBioPortal, TCGA Pan-Cancer Atlas