Variant dossier
IDH1 p.R132C
Static provenance dossier for a highlighted variant. Use the linked Explore state to compare related records across the full catalog.
DriverHotspotActionable
IDH1 p.R132C
No mechanism summary is present in the seed catalog for this record.
3.3%
17
2
- Coordinate
- GRCh37 chr2:209,113,113
- Cancer types
- DIFG Brain Lower Grade Glioma (TCGA, PanCancer Atlas)
- Pathway
- Not reported
- Therapy context
- Ivosidenib
- Clinical annotation
- N/A
- Citations
- 29625048, 29596782, 29622463, 29617662, 29625055, 29625050, 30643250, 32214244, 29625049, 29850653 +1
| Variant | Cancer | Evidence | Frequency | Sources |
|---|---|---|---|---|
| IDH1 p.R132H | DIFG | DriverHotspotActionable | 69.6% | TCGA Pan-Cancer Atlas, cBioPortal |
| IDH1 p.R132C | Not reported | DriverHotspotActionable | Not reported | Cancer Hotspots |
| IDH1 p.R132S | Not reported | DriverHotspotActionable | Not reported | Cancer Hotspots |
| IDH1 p.R132G | Not reported | DriverHotspotActionable | Not reported | Cancer Hotspots |
| IDH1 p.R132H | Not reported | DriverHotspotActionable | Not reported | Cancer Hotspots |
| IDH1 p.R132I | Not reported | DriverHotspotActionable | Not reported | Cancer Hotspots |
| IDH1 p.R132L | Not reported | DriverHotspotActionable | Not reported | Cancer Hotspots |
| IDH2 p.R172R | Not reported | DriverHotspotActionable | Not reported | Cancer Hotspots |