Variant dossier

IDH1 p.R132G

Static provenance dossier for a highlighted variant. Use the linked Explore state to compare related records across the full catalog.

DriverHotspotActionable

IDH1 p.R132G

No mechanism summary is present in the seed catalog for this record.

Not reportedreported frequency
766samples
1sources
Coordinate
No coordinate
Cancer types
Not reported
Pathway
Not reported
Therapy context
Ivosidenib
Clinical annotation
N/A
Citations
CancerHotspots:IDH1:R132
VariantCancerEvidenceFrequencySources
IDH1 p.R132H
substitution
DIFGDriverHotspotActionable69.6%TCGA Pan-Cancer Atlas, cBioPortal
IDH1 p.R132C
substitution
Not reportedDriverHotspotActionableNot reportedCancer Hotspots
IDH1 p.R132S
substitution
Not reportedDriverHotspotActionableNot reportedCancer Hotspots
IDH1 p.R132H
substitution
Not reportedDriverHotspotActionableNot reportedCancer Hotspots
IDH1 p.R132I
substitution
Not reportedDriverHotspotActionableNot reportedCancer Hotspots
IDH1 p.R132L
substitution
Not reportedDriverHotspotActionableNot reportedCancer Hotspots
IDH2 p.R172R
substitution
Not reportedDriverHotspotActionableNot reportedCancer Hotspots
IDH2 p.R172S
substitution
Not reportedDriverHotspotActionableNot reportedCancer Hotspots