Variant dossier
IDH2 p.R172S
Static provenance dossier for a highlighted variant. Use the linked Explore state to compare related records across the full catalog.
DriverHotspotActionable
IDH2 p.R172S
No mechanism summary is present in the seed catalog for this record.
Not reported
63
1
- Coordinate
- No coordinate
- Cancer types
- Not reported
- Pathway
- Not reported
- Therapy context
- Enasidenib
- Clinical annotation
- N/A
- Citations
- CancerHotspots:IDH2:R172
| Variant | Cancer | Evidence | Frequency | Sources |
|---|---|---|---|---|
| IDH1 p.R132H | DIFG | DriverHotspotActionable | 69.6% | TCGA Pan-Cancer Atlas, cBioPortal |
| IDH1 p.R132C | Not reported | DriverHotspotActionable | Not reported | Cancer Hotspots |
| IDH1 p.R132S | Not reported | DriverHotspotActionable | Not reported | Cancer Hotspots |
| IDH1 p.R132G | Not reported | DriverHotspotActionable | Not reported | Cancer Hotspots |
| IDH1 p.R132H | Not reported | DriverHotspotActionable | Not reported | Cancer Hotspots |
| IDH1 p.R132I | Not reported | DriverHotspotActionable | Not reported | Cancer Hotspots |
| IDH1 p.R132L | Not reported | DriverHotspotActionable | Not reported | Cancer Hotspots |
| IDH2 p.R172R | Not reported | DriverHotspotActionable | Not reported | Cancer Hotspots |